Ruoting Ma*†, Yu Yang*, Qiuyun Tu†, Ke Hu‡
Oncology Research, Vol.25, No.9, pp. 1495-1504, 2017, DOI:10.3727/096504017X14883287513729
Abstract T-box transcription factor 5 (TBX5), a member of the conserved T-box transcription factor family that functions in organogenesis and embryogenesis, has recently been identified as a critical player in cancer development. The aim of this study was to determine the role of TBX5 in non-small cell lung carcinoma (NSCLC).
Immunohistochemistry was used to detect the correlation between levels of TBX5 and clinicopathological
features of NSCLC patients in tissue microarray. Expression of TBX5 in NSCLC tissues and cell lines was
evaluated by quantitative PCR and Western blot. The role of TBX5 in regulating proliferation, colony formation,… More >
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