SHIQIN JIANG1,#, YICHUN TANG2,#, FENG MA3, YUCHUN NIU4,*, LEI SUN5,*
Oncology Research, Vol.33, No.1, pp. 213-224, 2025, DOI:10.32604/or.2024.046895
- 20 December 2024
Abstract Objective: Small cell lung cancer (SCLC) is commonly recognized as the most fatal lung cancer type. Despite substantial advances in immune checkpoint blockade therapies for treating solid cancers, their benefits are limited to a minority of patients with SCLC. In the present study, novel indicators for predicting the outcomes and molecular targets for SCLC treatment were elucidated. Methods: We conducted bioinformatics analysis to identify the key genes associated with tumor-infiltrating lymphocytes in SCLC. The functional role of the key gene identified in SCLC was determined both in vitro and in vivo. Results: A significant correlation was observed between… More >
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