Xiaopan Zou^1,2, Meiyang Sun³, Xin Jiang¹, Jingze Yu², Xiaomeng Li^4,*, Bingyu Nie^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.066662 - 30 December 2025

Abstract Objective: Triple-negative breast cancer (TNBC) is highly aggressive and lacks an effective targeted therapy. This study aimed to elucidate the functions and possible mechanisms of action of zinc finger miz-type containing 2 (ZMIZ2) and minichromosome maintenance complex component 3 (MCM3) in TNBC progression. Methods: The relationship between ZMIZ2 expression and clinical characteristics of TNBC was investigated. In vitro and in vivo experiments were performed to investigate the role of ZMIZ2 dysregulation in TNBC cell malignant behaviors. The regulatory relationship between ZMIZ2 and MCM3 was also explored. Transcriptome sequencing was performed to elucidate possible mechanisms underlying the ZMIZ2/MCM3… More >

Boudjema Bendaho¹, Abdelhak Mesbah¹, Zakaria Belabed^1,2,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2781-2805, 2025, DOI:10.32604/cmc.2025.069709 - 23 September 2025

Abstract A new quadrilateral finite element IQ4 is developed for the free vibration of carbon nanotube-reinforced composite (CNTRC) perforated plates with a central cutout. By enriching the membrane part and incorporating a projected shear technique, the IQ4 element is proposed to address the known limitations of the standard Q4 element, such as shear locking and limited consistency in the coupling of membrane-bending components. The proposed element is formulated within the FSDT-based framework and assessed through benchmark tests to verify its convergence and accuracy. The governing equations are obtained via the weak form of Hamilton’s principle. Particular… More >

Qiang Zhang^1,#, Dongsheng Gai^1,#, Yong Liu¹, Weiyang Liu¹, Pengcheng Fu¹, Xiwen Shao¹, Xuanhe Liang², Yanqiu Geng^1,*, Liying Guo^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 269-279, 2025, DOI:10.32604/phyton.2025.060551 - 24 January 2025

Abstract The yield of direct-seeded rice (DSR) was constrained by inadequate grain filling. Recent studies have indicated that paclobutrazol application plays a significant role in enhancing crop agronomic traits and increasing yield. This study aimed to examine the effects of paclobutrazol seed soaking (PSS) on non-structural carbohydrate accumulation and grain enrichment in DSR, potentially providing a theoretical foundation for achieving high-yield DSR cultivation. The experiment utilized two rice varieties, Jiyujing (JYJ) and Jijing305 (JJ305), with seeds soaked in paclobutrazol concentrations of 0 mg L⁻¹ and 100 mg L⁻¹. PSS demonstrated increased chlorophyll content, net photosynthetic rate, and… More >

Lixiang Wang¹, Longfei Wen^2,3, Rong Tian^2,3,*, Chun Feng^1,4,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.011137

Abstract The extended finite element method (XFEM) has been successful in crack analysis but faces challenges in modeling multiple cracks. One challenge is the linear dependence and ill-conditioning of the global stiffness matrix, while another is the geometric description for multiple cracks. To address the first challenge, the Improved XFEM (IXFEM) [1–9] is extended to handle multiple crack problems, effectively eliminating issues of linear dependence and ill-conditioning. Additionally, to overcome the second challenge, a novel level set templated cover cutting method (LSTCCM) [10] is proposed, which combines the advantages of the level set method and cover More >

Kaituo Jiao¹, Dongxu Han^2,*, Bo Yu²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-3, 2024, DOI:10.32604/icces.2024.011520

Abstract Motivated by the fractures being very thin compared to the size of rock matrix, utilizing the non-conforming grid is an efficient approach to simulate fluid flow in fractured porous media. The embedded discrete fracture model (EDFM) is the typical one that using the conforming grid and modelled based on the finite volume method (FVM) framework. The EDFM maintains advantages of mass conservation and low computational complexity, but it cannot characterize blocking fractures and has a low accuracy on the mass exchange between fractures and matrix [1]. In our previous work [2], we developed the enriched-EDFM… More >

Oncology Research Editorial Office

Oncology Research, Vol.32, No.11, pp. 1817-1817, 2024, DOI:10.32604/or.2024.056892 - 16 October 2024

Abstract This article has no abstract. More >

Huijie Huang¹, Jingfa Li^2,*, Xu Sun^1,*, Bo Yu²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011026

Abstract The blending of hydrogen into natural gas provides an optimal solution for large-scale hydrogen transport, utilizing existing natural gas pipelines for mixed conveyance. The thermophysical parameters of hydrogen-enriched natural gas (HENG) significantly influence the design and operation of gas transmission networks. Therefore, accurate prediction of the thermophysical parameters of HENG is crucial. However, due to the effects of hydrogen blending, the adaptability of commonly used equations of state (EoSs) to HENG remains uncertain, especially at high hydrogen blending ratios (HBRs). In this study, the accuracy of the EoSs of PR, BWRS, AGA8-92DC, and GERG-2008 is… More >

Xiaojun Li, Fuyong Su^*

Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 719-732, 2024, DOI:10.32604/fhmt.2024.051950 - 11 July 2024

Abstract In order to study the effect of oxygen-enriched combustion technology on the temperature field and NO emission in the continuous heating furnace, this paper studies the oxygen-enriched combustion of a pushing steel continuous heating furnace in a domestic company. This study utilizes numerical simulation method, establishes the mathematical models of flow, combustion and NO generation combustion process in the furnace and analyzes the heat transfer process and NO generation in the furnace under different air oxygen content and different wind ratio. The research results show that with the increase of oxygen content in the air, More > Graphic Abstract

Zonglin Li^1,2, Zhenyu Gao², Yijun Liu^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2159-2175, 2024, DOI:10.32604/cmes.2023.030920 - 15 December 2023

Abstract The boundary element method (BEM) is a popular method for solving acoustic wave propagation problems, especially those in exterior domains, owing to its ease in handling radiation conditions at infinity. However, BEM models must meet the requirement of 6–10 elements per wavelength, using the conventional constant, linear, or quadratic elements. Therefore, a large storage size of memory and long solution time are often needed in solving higher-frequency problems. In this work, we propose two new types of enriched elements based on conventional constant boundary elements to improve the computational efficiency of the 2D acoustic BEM.… More > Graphic Abstract

Naima Krarraz^1,*, Amina Sabeur¹, Khadidja Safer², Ahmed Ouadha¹

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.1, pp. 79-96, 2024, DOI:10.32604/fdmp.2023.026238 - 08 November 2023

Abstract Any biogas produced by the anaerobic fermentation of organic materials has the advantage of being an environmentally friendly biofuel. Nevertheless, the relatively low calorific value of such gases makes their effective utilization in practical applications relatively difficult. The present study considers the addition of hydrogen as a potential solution to mitigate this issue. In particular, the properties of turbulent diffusion jet flames and the related pollutant emissions are investigated numerically for different operating pressures. The related numerical simulations are conducted by solving the RANS equations in the frame of the Reynolds Stress Model in combination More > Graphic Abstract