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    ARTICLE

    miR-326 Inhibits Gastric Cancer Cell Growth Through Downregulating NOB1

    Sheqing Ji, Bin Zhang, Ye Kong, Fei Ma, Yawei Hua

    Oncology Research, Vol.25, No.6, pp. 853-861, 2017, DOI:10.3727/096504016X14759582767486

    Abstract MicroRNAs (miRNAs) play a crucial role in the development and progression of human cancers, including gastric cancer (GC). The discovery of miRNAs may provide a new and powerful tool for studying the mechanism, diagnosis, and treatment of GC. In this study, we aimed to investigate the role of miR-326 in the development and progression of GC. Quantitative PCR (qPCR) was used to measure the expression level of miR-326 in GC tissues and cell lines. We found that miR-326 was significantly downregulated during GC. In addition, overexpression of miR-326 inhibited GC cell proliferation. Fluorescence-activated cell sorting More >

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