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  • Open Access

    VIEWPOINT

    Future of the current anticoronaviral agents: A viewpoint on the validation for the next COVIDs and pandemics

    AMGAD M. RABIE*

    BIOCELL, Vol.47, No.10, pp. 2133-2139, 2023, DOI:10.32604/biocell.2023.030057 - 08 November 2023

    Abstract Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease still represents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists, virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviral therapies that are broadly effective against the different species/strains of the coronaviruses in general, not only against the current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2 “SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, including More > Graphic Abstract

    Future of the current anticoronaviral agents: A viewpoint on the validation for the next COVIDs and pandemics

  • Open Access

    EDITORIAL

    Des données de la recherche aux modèles d’interventions : intervenir avec toutes les parties prenantes

    Louise Potvin1, Grégory Ninot2,3, Sabine Dutheil4, Anne-Fleur Guillemin5, Jérôme Foucaud5,*

    Psycho-Oncologie, Vol.17, No.3, pp. 109-112, 2023, DOI:10.32604/po.2023.045104 - 30 September 2023

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Application of Wavelength Selection Combined with DS Algorithm for Model Transfer between NIR Instruments

    Honghong Wang1, Zhixin Xiong1,*, Yunchao Hu1, Zhijian Liu1, Long Liang2

    Journal of Renewable Materials, Vol.11, No.6, pp. 2713-2727, 2023, DOI:10.32604/jrm.2023.025817 - 27 April 2023

    Abstract This study aims to realize the sharing of near-infrared analysis models of lignin and holocellulose content in pulp wood on two different batches of spectrometers and proposes a combined algorithm of SPA-DS, MCUVE-DS and SiPLS-DS. The Successive Projection Algorithm (SPA), the Monte-Carlo of Uninformative Variable Elimination (MCUVE) and the Synergy Interval Partial Least Squares (SiPLS) algorithms are respectively used to reduce the adverse effects of redundant information in the transmission process of the full spectrum DS algorithm model. These three algorithms can improve model transfer accuracy and efficiency and reduce the manpower and material consumption… More >

  • Open Access

    ARTICLE

    Evaluating the Potentials of PLSR and SVR Models for Soil Properties Prediction Using Field Imaging, Laboratory VNIR Spectroscopy and Their Combination

    Emna Karray1, Hela Elmannai2,*, Elyes Toumi1, Mohamed Hedi Gharbia3, Souham Meshoul2, Hamouda Aichi4, Zouhaier Ben Rabah1

    CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.2, pp. 1399-1425, 2023, DOI:10.32604/cmes.2023.023164 - 06 February 2023

    Abstract Pedo-spectroscopy has the potential to provide valuable information about soil physical, chemical, and biological properties. Nowadays, we may predict soil properties using VNIR field imaging spectra (IS) such as Prisma satellite data or laboratory spectra (LS). The primary goal of this study is to investigate machine learning models namely Partial Least Squares Regression (PLSR) and Support Vector Regression (SVR) for the prediction of several soil properties, including clay, sand, silt, organic matter, nitrate NO3-, and calcium carbonate CaCO3, using five VNIR spectra dataset combinations (% IS, % LS) as follows: C1 (0% IS, 100% LS),… More > Graphic Abstract

    Evaluating the Potentials of PLSR and SVR Models for Soil Properties Prediction Using Field Imaging, Laboratory VNIR Spectroscopy and Their Combination

  • Open Access

    ARTICLE

    Functional Nonparametric Predictions in Food Industry Using Near-Infrared Spectroscopy Measurement

    Ibrahim M. Almanjahie1,2,*, Omar Fetitah3, Mohammed Kadi Attouch3, Tawfik Benchikh3,4

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 6307-6319, 2023, DOI:10.32604/cmc.2023.033441 - 28 December 2022

    Abstract Functional statistics is a new technique for dealing with data that can be viewed as curves or images. Parallel to this approach, the Near-Infrared Reflectance (NIR) spectroscopy methodology has been used in modern chemistry as a rapid, low-cost, and exact means of assessing an object’s chemical properties. In this research, we investigate the quality of corn and cookie dough by analyzing the spectroscopic technique using certain cutting-edge statistical models. By analyzing spectral data and applying functional models to it, we could predict the chemical components of corn and cookie dough. Kernel Functional Classical Estimation (KFCE),… More >

  • Open Access

    REVIEW

    Is autophagy induction by PARP inhibitors a target for therapeutic benefit?

    AHMED M. ELSHAZLY1,2, TUONG VI V. NGUYEN1, DAVID A. GEWIRTZ1,*

    Oncology Research, Vol.30, No.1, pp. 1-12, 2022, DOI:10.32604/or.2022.026459 - 06 December 2022

    Abstract PARP inhibitors have proven to be effective in conjunction with conventional therapeutics in the treatment of various solid as well as hematologic malignancies, particularly when the tumors are deficient in DNA repair pathways. However, as the case with other chemotherapeutic agents, their effectiveness is often compromised by the development of resistance. PARP inhibitors have consistently been reported to promote autophagy, a process that maintains cellular homeostasis and acts as an energy source by the degradation and reutilization of damaged subcellular organelles and proteins. Autophagy can exhibit different functional properties, the most prominent being cytoprotective. In More >

  • Open Access

    ARTICLE

    Insight into the characteristics of an important evolutionary model bird (Geospiza magnirostris) mitochondrial genome through comparison

    ZHENGGANG XU1,2,3, LIANG WU3, JIAHAO CHEN1, YUNLIN ZHAO3, CHONGXUAN HAN1, TIAN HUANG2, GUIYAN YANG1,*

    BIOCELL, Vol.46, No.7, pp. 1733-1746, 2022, DOI:10.32604/biocell.2022.015784 - 17 March 2022

    Abstract Darwin’s finches are the most classic case of evolution. Early studies on the evolution of this species were mainly based on morphology. Until now, the mitochondrial genome of Geospiza magnirostris has been sequenced and the study explored the characteristics of the complete genome of G. magnirostris and verified the evolutionary position of it. The 13 PCGs initiated by ATN codons. The stop codons of three PCGs (ND2, COX3 and ND4) were incomplete, with only T- or TA- replacing complete form TAA or TAG. All the tRNA genes expressed a typical cloverleaf secondary structure, except for tRNASer1(AGY), whose dihydrouridine (DHU)… More >

  • Open Access

    MINI REVIEW

    Therapeutic Potential of the Medicinal Plant Tinospora cordifolia–Minireview

    Lohanathan Bharathi Priya1,#, Balamuralikrishnan Balasubramanian2,#, Balamurugan Shanmugaraj3, Shanmugam Subbiah4, Rouh-Mei Hu5, Chih-Yang Huang6,7,8,9,*, Rathinasamy Baskaran5,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.6, pp. 1129-1140, 2022, DOI:10.32604/phyton.2022.017707 - 14 February 2022

    Abstract For thousands of years, plant based herbal medicines have been utilized by millions of people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as the Chinese, African and Indian medical systems, like Siddha, Ayurveda, Unani, and Homeopathy. Tinospora cordifolia (TC) is a medicinal plant belonging to the family Menispermaceae. It is a big deciduous, climbing shrub growing prevalently in the tropical part of Indian subcontinent regions such as India, Pakistan, Nepal, Bhutan, Bangladesh and Srilanka, and in Myanmar, and China. Guduchi, Giloy, Shindilkodi, and Amritha are all the… More >

  • Open Access

    ARTICLE

    Hemodynamic Response Detection Using Integrated EEG-fNIRS-VPA for BCI

    Arshia Arif1, M. Jawad Khan1,2,*, Kashif Javed1, Hasan Sajid1,2, Saddaf Rubab1, Noman Naseer3, Talha Irfan Khan4

    CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 535-555, 2022, DOI:10.32604/cmc.2022.018318 - 07 September 2021

    Abstract For BCI systems, it is important to have an accurate and less complex architecture to control a device with enhanced accuracy. In this paper, a novel methodology for more accurate detection of the hemodynamic response has been developed using a multimodal brain-computer interface (BCI). An integrated classifier has been developed for achieving better classification accuracy using two modalities. An integrated EEG-fNIRS-based vector-phase analysis (VPA) has been conducted. An open-source dataset collected at the Technische Universität Berlin, including simultaneous electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) signals of 26 healthy participants during n-back tests, has been… More >

  • Open Access

    ARTICLE

    Cluster Analysis for IR and NIR Spectroscopy: Current Practices to Future Perspectives

    Simon Crase1,2, Benjamin Hall2, Suresh N. Thennadil3,*

    CMC-Computers, Materials & Continua, Vol.69, No.2, pp. 1945-1965, 2021, DOI:10.32604/cmc.2021.018517 - 21 July 2021

    Abstract Supervised machine learning techniques have become well established in the study of spectroscopy data. However, the unsupervised learning technique of cluster analysis hasn’t reached the same level maturity in chemometric analysis. This paper surveys recent studies which apply cluster analysis to NIR and IR spectroscopy data. In addition, we summarize the current practices in cluster analysis of spectroscopy and contrast these with cluster analysis literature from the machine learning and pattern recognition domain. This includes practices in data pre-processing, feature extraction, clustering distance metrics, clustering algorithms and validation techniques. Special consideration is given to the More >

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