FUJI YANG1, YAN HUANG1, YOUWEN TAN2,*, YONGMIN YAN1,*
BIOCELL, Vol.46, No.2, pp. 389-400, 2022, DOI:10.32604/biocell.2021.015899
- 20 October 2021
Abstract Nonalcoholic fatty liver disease (NAFLD) is a long-lasting condition that affects the liver, destroying its
function. Liver injury can cause steatosis and inflammation, and further activation of hepatic stellate cells (HSCs)
often leads to the development of nonalcoholic liver fibrosis. The patient with NAFLD is at risk of developing
advanced liver disease and complications, such as liver failure, hepatocellular carcinoma (HCC), and portal
hypertension. Although our understanding of the cellular and molecular mechanisms of NAFLD has greatly improved
in recent years, treatment remains limited. Analysis and characterization of protein posttranslational modifications
(PTMs) could improve our More >
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