Qinglong Kong, Nan Shu, Jun Li, Ning Xu
Oncology Research, Vol.26, No.5, pp. 735-741, 2018, DOI:10.3727/096504017X15021536183490
Abstract Lung cancer is the leading cause of deaths due to cancer. Studies suggest an important role of microRNAs
(miRNAs) in a variety of cancers, including lung cancer. In the present study, we evaluated the role of miR-
641 in human lung cancer A549 cells. Quantitative RT-PCR and Western blot were used to measure mRNA
and protein expression, respectively. Cell viability and cell apoptosis were respectively measured by MTT
assay and flow cytometry. In addition, luciferase activity assay was used to identify the target of miR-641.
The expression of miR-641 was downregulated in lung cancer tissues More >
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