Huihui Shi^1,#, Lei Chen^2,#, Juan Huang^3,#, Xuejing Lin², Lei Huang⁴, Min Tang⁴, Kai Lu^5,*, Wenchao Wang^4,*, Maoling Zhu^1,§,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068737 - 30 December 2025

Abstract Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. This study aimed to identify key genes involved in HCC development and elucidate their molecular mechanisms, with a particular focus on mitochondrial function and apoptosis. Methods: Differential expression analyses were performed across three datasets—The Cancer Genome Atlas (TCGA)-Liver Hepatocellular Carcinoma (LIHC), GSE36076, and GSE95698—to identify overlapping differentially expressed genes (DEGs). A prognostic risk model was then constructed. Cysteine/serine-rich nuclear protein 1 (CSRNP1) expression levels in HCC cell lines were assessed via western blot (WB) and quantitative reverse transcription polymerase chain reaction (qRT-PCR).… More > Graphic Abstract

Xuanhong Wang¹, Hongyu Guo¹, Jiazhen Li¹, Mingchen Wang¹, Xian Wang¹, Yijun Zhang^2,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-19, 2026, DOI:10.32604/cmc.2025.069482 - 10 November 2025

Abstract Over the past decade, large-scale pre-trained autoregressive and diffusion models rejuvenated the field of text-guided image generation. However, these models require enormous datasets and parameters, and their multi-step generation processes are often inefficient and difficult to control. To address these challenges, we propose CAFE-GAN, a CLIP-Projected GAN with Attention-Aware Generation and Multi-Scale Discrimination, which incorporates a pre-trained CLIP model along with several key architectural innovations. First, we embed a coordinate attention mechanism into the generator to capture long-range dependencies and enhance feature representation. Second, we introduce a trainable linear projection layer after the CLIP text… More >

Kunpeng Zhou¹, Tao Wu^1,*, Jia Zhang²

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-27, 2026, DOI:10.32604/cmc.2025.068160 - 10 November 2025

Abstract Over the past few years, video live streaming has gained immense popularity as a leading internet application. In current solutions offered by cloud service providers, the Group of Pictures (GOP) length of the video source often significantly impacts end-to-end (E2E) latency. However, designing an optimized GOP structure to reduce this effect remains a significant challenge. This paper presents two key contributions. First, it explores how the GOP length at the video source influences E2E latency in mainstream cloud streaming services. Experimental results reveal that the mean E2E latency increases linearly with longer GOP lengths. Second, More >

Xiaoqin Zheng¹, Yuqing Wan¹, Qian Zhang², Liqin He², Shihao Tang¹, Qiguo Zhuang², Lihua Wang^2,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3879-3892, 2025, DOI:10.32604/phyton.2025.073229 - 29 December 2025

Abstract To investigate endogenous hormone changes in “Hongyang” kiwifruit from overwintering buds to floral morphogenesis (bell-shaped flowering stage), systematic observations were conducted during the undifferentiated stage, axillary bud differentiation stage, and floral morphogenesis stage from late November 2023 to early April 2024. Paraffin sectioning was employed to examine floral bud morphology, while LC-MS targeted metabolomics quantified changes in 15 endogenous hormones across 8 classes. Results indicated floral bud differentiation commenced from late January to early February and concluded by mid-April, spanning approximately 70 days. Approximately 33 days after axillary bud initiation marked the axillary bud primordium… More >

Sapan Pandya^*

Journal of Cyber Security, Vol.7, pp. 637-651, 2025, DOI:10.32604/jcs.2025.073670 - 24 December 2025

Abstract Ransomware has evolved from opportunistic malware into a global economic weapon, crippling critical services and extracting billions in illicit revenue. While most research has centered on enterprise networks and healthcare systems, an equally vulnerable frontier is emerging in lottery and betting kiosks—self-service financial Internet of Things (IoT) devices that handle billions of dollars annually. These terminals operate unattended, rely on legacy operating systems, and interact with sensitive transactional data, making them prime ransomware targets. This paper introduces a Resilient Security Framework (RSF) for kiosks under ransomware threat conditions. RSF integrates three defensive layers: (1) prevention… More >

Roland Mangold, Timea Teglas^*

BIOCELL, Vol.49, No.12, pp. 2239-2244, 2025, DOI:10.32604/biocell.2025.069925 - 24 December 2025

Abstract The quality of life in older adulthood is greatly influenced by cognitive aging, which in turn is affected by nutrition, especially as it relates to hippocampal function. Although the link between hippocampal function and nutrition is defined, the exact mechanics are still unknown. The commentary addresses how docosahexaenoic acid (DHA) contributes to age-related cognitive decline and may play a role in promoting neurogenesis and neuroplasticity on the molecular level. The current challenge to our understanding is to investigate how DHA influences hippocampal function and cognitive aging, which would be possible and even more detailed with More >

Nattawat Mahasuwanchai, Thippakorn Udtaranakron, Kasan Chanto, Tawich Pulngern^*

Journal of Renewable Materials, Vol.13, No.12, pp. 2453-2478, 2025, DOI:10.32604/jrm.2025.02025-0137 - 23 December 2025

Abstract This research investigates the behavior of sandwich glued laminated bamboo (Glubam) structures with a core formed by biodegradable plastic fibers, specifically polylactic acid (PLA), fabricated using 3D printing technology. The influence of various fiber printing orientations (0° and 45/135°) on tensile and compressive properties was investigated. The experimental results indicated that polylactic acid with calcium carbonate (PLA+) printed unidirectionally and aligned with the loading direction (0°) exhibits superior tensile and compressive strengths compared to specimens printed bidirectionally at 45/135°. Furthermore, the effect of additives on bioplastics of carbon fiber (PLA-CF) and glass fiber (PLA-GF) additives… More > Graphic Abstract

Nada Zaari Jabri¹, Mohamed Ait-El-Mokhtar^1,*, Fadoua Mekkaoui¹, Najwa Rabah¹, Ilham Amghar¹, Ghizlane Diria², Abdelaziz Hmyene¹

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3687-3701, 2025, DOI:10.32604/phyton.2025.071634 - 01 December 2025

Abstract Cadmium (Cd) contamination is a major environmental stressor that adversely affects crop germination and early development. This study assessed the impact of increasing Cd concentrations (0.125 to 1 g/L) on seed germination and early seedling growth in three bread wheat (Triticum aestivum L.) cultivars: Achtar, Lina, and Snina. The results revealed a clear dose-dependent inhibitory effect of Cd. Germination percentage (GP) significantly declined with increasing Cd levels, while mean germination time was progressively delayed, particularly at higher concentrations. Vigor index (VI) also showed significant reductions, reflecting compromised seedling establishment. Morphological traits, especially shoot and root lengths,… More >

Rawabi S. Altuwayjiri, Ibtesam S. Almami^*

Oncology Research, Vol.33, No.12, pp. 3923-3943, 2025, DOI:10.32604/or.2025.070104 - 27 November 2025

Abstract Objective: Testicular germ cell tumors (TGCTs) represent the most common malignancy among young men aged 20–40 years. Transglutaminase 7 (TG7), encoded by TGM7, is a poorly characterized enzyme whose function in TGCT remains unknown. This study aimed to assess TG7 expression in clinical specimens and investigate its functional role in a testicular germ cell tumor cell line (NT2/D1). Methods: TG7 protein expression was evaluated in clinical testicular tissue samples via immunohistochemistry (IHC) and immunofluorescence (IF). Functional analysis was conducted in the NT2/D1 human testicular cancer cell line using Dicer-substrate small interfering RNAs (DsiRNAs) targeting TG7. Gene… More >

Zhaoqi Li, Xuan Liu, Hengkong Zhao, Zhen Zhang^*, Yan Li

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-1, 2025, DOI:10.32604/icces.2025.012239

Abstract The growing use of ultra-thick composite laminates in aerospace structures demands a deeper understanding of their unique damage mechanisms under tensile loading, which differ significantly from those of thin laminates. This study introduces a novel 3D progressive damage model combining solid elements, the LaRC05 3D failure criterion (enhanced with through-thickness in-situ strengthening effects), and a mixed-mode cohesive zone model (CZM) to predict interlaminar delamination. The model captures the interaction between in-plane damage and through-thickness failure modes in open-hole ultra-thick composites, and addresses stress redistribution, localized buckling, delamination migration, and in-situ strength enhancement. Mesh sensitivity analysis… More >