Zhiying Su*1, Hua Yang†1, Min Zhao*,‡ Yanlong Wang*, Guoyi Deng*, Ruixin Chen*
Oncology Research, Vol.25, No.1, pp. 137-145, 2017, DOI:10.3727/096504016X14732772150262
Abstract MicroRNA-92a (miR-92a) generally plays a promoting role in human cancers, but the underlying mechanism
in cervical cancer remains unclear. Here we studied the expression and clinical significance of miR-92a in
cervical cancer, as well as the regulatory mechanism in the proliferation of cervical cancer cells. Our data indicated that miR-92a was significantly upregulated in cervical cancer tissues compared to their matched adjacent
nontumor tissues (ANTs), and the increased miR-92a levels were significantly associated with a higher grade,
lymph node metastasis, and advanced clinical stage in cervical cancer. In vitro study revealed that inhibition
of miR-92a… More >
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