Jian Shen, Minzhe Li
Oncology Research, Vol.26, No.9, pp. 1401-1409, 2018, DOI:10.3727/096504018X15188747585738
Abstract Accumulated studies have strongly implicated aberrantly expressed microRNAs (miRNAs) in carcinogenesis
and cancer progression of various cancers, including colorectal cancer (CRC). Hence, a comprehensive study
of miRNAs and their association with CRC may be a promising therapeutic method for patients with this
malignancy. MicroRNA-744 (miR-744) is abnormally expressed in several types of human cancer. Thus far,
little is known about the expression, biological roles, and exact mechanisms of miR-744 in CRC. Thus, the
present study measured the expression level of miR-744 and investigated its roles and associated molecular
mechanisms in CRC. This study demonstrated that… More >