Wei Wu*, Linyan He†‡, Yan Huang*, Likun Hou*, Wei Zhang*, Liping Zhang*, Chunyan Wu*
Oncology Research, Vol.27, No.8, pp. 879-887, 2019, DOI:10.3727/096504018X15451308507747
Abstract An increasing number of studies have demonstrated that microRNAs (miRNAs) may play key roles in various
cancer carcinogenesis and progression, including non-small cell lung cancer (NSCLC). However, the expressions, roles, and mechanisms of miR-510 in NSCLC have, up to now, been largely undefined. In vivo assay
showed that miR-510 was upregulated in NSCLC tissues compared with that in adjacent nontumor lung tissues.
miR-510 expression was significantly correlated with TNM stage and lymph node metastasis. In vitro assay
indicated that expressions of miR-510 were also increased in NSCLC cell lines. Downregulation of miR-510
suppressed NSCLC cell More >
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