Yun Qin*, Yu Wang†‡§, Dongbo Liu¶
Oncology Research, Vol.28, No.4, pp. 357-369, 2020, DOI:10.3727/096504020X15844389264424
Abstract It has been reported that kindlin-3 expression is closely associated with progression of many cancers and
microRNA (miRNA) processing. However, the effects and precise mechanisms of kindlin-3 in acute myeloid
leukemia (AML) have not been well clarified. Our study aimed to explore the interaction between kindlin-3
and miR-4792 in AML. In our study, we found that the expression of kindlin-3 was dramatically increased in
AML samples and cell lines, and the miR-4792 level was significantly downregulated. Interestingly, the low
miR-4792 level was closely associated with upregulated kindlin-3 expression in AML samples. Moreover,
introduction of miR-4792 More >
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