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  • Open Access

    ARTICLE

    MicroRNA-212 Targets Mitogen-Activated Protein Kinase 1 to Inhibit Proliferation and Invasion of Prostate Cancer Cells

    Bo Hu*, Xunbo Jin*, Jianbo Wang

    Oncology Research, Vol.26, No.7, pp. 1093-1102, 2018, DOI:10.3727/096504018X15154112497142

    Abstract Prostate cancer (PCa) is the second most commonly diagnosed malignancy and the fifth leading cause of cancer-related deaths in males worldwide. MicroRNAs (miRNAs) may serve as important regulators in PCa occurrence and development. Therefore, understanding the expression and functions of PCa-related miRNAs may be beneficial for the identification of novel therapeutic methods for patients with PCa. In this study, miRNA-212 (miR-212) was evidently downregulated in PCa tissues and several PCa cell lines. Functional assays showed that the resumption of miR-212 expression attenuated cell proliferation and invasion and increased the apoptosis of PCa. In addition, mitogen-activated More >

  • Open Access

    ARTICLE WITHDRAWN

    [ARTICLE WITHDRAWN] Long Noncoding RNA KCNQ1OT1 Accelerates the Progression of Ovarian Cancer via MicroRNA-212-3/LCN2 Axis

    Lu, Xiaoqin1, Wang, Fuying1, Fu, Meizhou2, Li, Yuankun1, Wang, Lijun1

    Oncology Research, Vol.28, No.2, pp. 135-146, 2020, DOI:10.3727/096504019X15719983040135

    Abstract This article was wihdrawn by the authors with the following Withdrawal Statement - The integrity of the current study is not acceptable. The authors intend to enrich the study to make it more valuable. Thus, the authors want to withdraw the current study. Please accept our apologies for this inconvenience and we hope for your understanding. Yours sincerely (on behalf of the authors), Xiaoqin Lu. More >

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