Xianbiao Shi, Xiaoqiao Tang, Lei Su
Oncology Research, Vol.26, No.6, pp. 869-878, 2018, DOI:10.3727/096504017X15123838050075
Abstract This study aimed to investigate the effect of long noncoding RNA PTENP1 in the development of breast cancer
(BC). Quantitative real-time PCR was utilized to determine the expression of PTENP1 in tissues and cell lines.
pcDNA3.1 and shRNA were used to over- and low-express PTENP1 in BC cell lines, and miR-19b mimic
and inhibitor were utilized to over- and low-express miR-19b. Then the abilities of cell survival, apoptosis,
migration, and invasion were assessed in BC cells with different expression levels of PTENP1 and miR-19b.
The expression of PTENP1 was significantly downregulated in both BC tissues More >
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