Peng Guo*, Guohui Zhang*†, Jialin Meng‡, Qian He*, Zhihui Li†, Yawei Guan†
Oncology Research, Vol.26, No.7, pp. 1083-1091, 2018, DOI:10.3727/096504018X15152085755247
Abstract Bladder cancer (BC) is one of the leading causes of cancer-related deaths in the world. Long noncoding RNA
(lncRNA) taurine-upregulated gene 1 (TUG1) plays an important role in the development and progression
of numerous cancers, including BC. However, the exact role of TUG1 in modulating BC progression is still
poorly known. In this study, we found that TUG1 was upregulated and microRNA-29c (miR-29c) was downregulated in BC tissues and cell lines. Overexpression of TUG1 promoted the cell proliferation of T24 and
EJ cells, whereas TUG1 knockdown had the opposite effect. Upregulation of TUG1 obviously facilitated… More >
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