Pingkan Aditiawati¹, Kamarisima¹, Rudi Dungani^1,*, Tirto Prakoso², Neil Priharto¹, Muhammad Iqbal Ar-Razy Suwardi¹, Muhammad Rizki Ramdhani¹, Maya Fitriyanti¹, Dzulianur Mutsla¹, Widya Fatriasari³

Journal of Renewable Materials, Vol.14, No.1, 2026, DOI:10.32604/jrm.2025.02025-0113 - 23 January 2026

Abstract This study aimed to produce and characterize mycelium leather (Mylea) derived from oil palm empty fruit bunch (OPEFB). Variations in OPEFB composition (10%, 20%, 30%, and 40%) were tested using a 10% w/w Ganoderma lucidum inoculum. The mycelium underwent boiling, plasticization, drying, pressing, waxing, and Tencel fabric reinforcement to form Mylea. The physical, mechanical, and flammability properties of OPEFB-based Mylea were evaluated as a potential animal leather substitute. The highest tensile strength (8.47 MPa) was observed in the 0% OPEFB sample due to reinforcement with the Tencel fabric layer. Meanwhile, the 20% OPEFB sample after drying More > Graphic Abstract

Ilze Irbe^1,*, Laura Andze¹, Inese Filipova^1,2

Journal of Renewable Materials, Vol.13, No.11, pp. 2139-2154, 2025, DOI:10.32604/jrm.2025.02025-0107 - 24 November 2025

Abstract Growing environmental concerns and the need for sustainable alternatives to synthetic materials have led to increased interest in bio-based composites. This study investigates the development and characterization of sustainable egg packaging waste (EPW) biocomposites derived from recycled wood fibers and fungal mycelium filaments as a natural binder. Three formulations were prepared using EPW as the primary substrate, with and without the addition of hemp shives and sawdust as co-substrates. The composites were evaluated for granulometry, density, mechanical strength, hygroscopic behavior, thermal conductivity, and fire performance using cone calorimetry. Biocomposites, composed exclusively of egg packaging waste,… More >

Ceren Ayşe Bayram^*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3283-3295, 2025, DOI:10.32604/phyton.2025.073047 - 29 October 2025

Abstract In semi-arid regions where climatic limitations hinder open-field vegetable production, greenhouse-based lettuce (Lactuca sativa L.) cultivation plays a vital role in ensuring off-season supply. In this study, the potential of sustainable input combinations was evaluated to enhance lettuce productivity, quality, and profitability under unheated greenhouse conditions in Southeastern Türkiye. Treatments included farmer practice and a mycorrhizal biofertilizer (ERS, a water-soluble arbuscular mycorrhizal fungus product) applied alone or in combination with organic-based biostimulants (IS and NM). Evaluated parameters were plant height, leaf pigmentation (a*, h°), SPAD values, vitamin C, nitrogen and phosphorus content, and gross margin. The More >

Lina Corgiolu, Giuseppe Giannaccare^*, Alberto Cuccu

Oncology Research, Vol.33, No.10, pp. 2725-2740, 2025, DOI:10.32604/or.2025.067221 - 26 September 2025

Abstract Topical chemotherapy is increasingly used to treat ocular surface tumors as a primary therapy and an adjuvant treatment after surgical excision. The most employed topical agents include mitomycin C (MMC), 5-fluorouracil (5-FU), and interferon alpha-2b (IFNα2b), each with distinct mechanisms of action, efficacy profiles, and toxicity risks. Although these agents offer effective tumor control and allow for a non-invasive approach in many cases, ocular surface complications requiring medical or surgical management can occur. This summarizes the adverse effect and outilines practical strategies for their prevention and treatment. MMC is the most potent agent but also… More >

Stanislav Kotlyarov^1,*, Dmitry Oskin²

BIOCELL, Vol.49, No.9, pp. 1631-1661, 2025, DOI:10.32604/biocell.2025.066675 - 25 September 2025

Abstract Chronic obstructive pulmonary disease (COPD) and respiratory tuberculosis are important respiratory problems. Meeting together, these diseases can mutually worsen the severity of clinical manifestations and negatively affect prognosis. COPD and tuberculosis share a number of common risk factors and pathogenetic mechanisms involving various immune and non-immune cells. Inflammation, hypoxia, oxidative stress, and lung tissue remodeling play an important role in the comorbid course of COPD and respiratory tuberculosis. These mechanisms are of diagnostic interest and are promising therapeutic targets. Thus, the aim of the current review is to discuss the mechanisms of the comorbid course More >

Cheng Yong^1,2,3,4,5, Enhui Sun^1,*, Xiaodong Fan^1,4, Zhiping Zhang⁵, Jing Zhang¹, Ling Chen¹, Ping Qu¹, Qiujun Wang¹, Hongying Huang¹, Hongmei Jin¹, Mingjie Guan^4,*

Journal of Renewable Materials, Vol.13, No.9, pp. 1803-1817, 2025, DOI:10.32604/jrm.2025.02025-0059 - 22 September 2025

Abstract Long-time fermentation has always been one of the reasons restricting the development of straw biological pulping. This study aimed to develop a novel straw pulp film with shortened solid-state fermentation time with less than 20% mass loss rate by bio-pulping synergistic treatment of straw fibers with deep eutectic solvent (DES) and Streptomyces rochei (S. rochei). Results illustrated that at 3% S. rochei concentration with 7-day fermentation, both cellulose and hemicellulose enzyme activities of the treated rice straw fiber reached peak values with a fiber mass loss rate of 17.01%. Microstructural morphology revealed that S. rochei colonization initiated on straw… More > Graphic Abstract

Alehegn Atalay Birlie^*

Journal of Renewable Materials, Vol.13, No.9, pp. 1783-1802, 2025, DOI:10.32604/jrm.2025.02025-0039 - 22 September 2025

Abstract This study explores vegan leather, an eco-friendly substitute for conventional animal-derived leather. Using materials like polyurethane, pineapple leaves, cork, and recycled plastics, vegan leather aims to transform the fashion industry and consumer products while addressing environmental concerns. Despite its advantages, challenges related to availability and durability persist. The booming market for vegan leather is expected to reach billions of dollars, reflecting a broader societal shift towards sustainable and cruelty-free alternatives. The review traces the historical development of vegan leather from its origins in Germany to modern innovations like Mylo and Piñatex. By comparing these materials More >

Siliang Liu^1,#, Hong Tang^2,#, Ying Xia¹, Zhengtao Yu¹, Ning Gao^1,*

BIOCELL, Vol.49, No.7, pp. 1245-1264, 2025, DOI:10.32604/biocell.2025.064396 - 25 July 2025

Abstract Objectives: NOD-like receptor family pyrin domain-containing (NLRP) 1-mediated pyroptosis plays a key role in the pathogenesis of cerebral ischemia-reperfusion injury (CIRI). C-Myc is reported to play a major role in CIRI. However, the mechanism remains unclear. This study aimed to investigate whether c-Myc affects CIRI by regulating Serine/Arginine-rich Splicing Factor 1 (SRSF1)/NLRP1-mediated pyroptosis. Methods: Oxygen-glucose deprivation/reperfusion (OGD/R) induced neuroblastoma cells for the establishment of an in vitro CIRI model. The levels of c-Myc and SRSF1, cell viability, the expression of pyroptosis-related factors, and the interaction between SRSF1 and NLRP1 were evaluated. Results: The expression of c-Myc and… More >

KEFAN LIU¹, XIAOSONG WANG¹, XIN YANG¹, BOWEN SHI¹, LEI XING^2,*, JUNXIA CHEN^1,*

Oncology Research, Vol.33, No.7, pp. 1709-1722, 2025, DOI:10.32604/or.2025.061721 - 26 June 2025

Abstract Background: Accumulating studies have shown the important role of circular RNAs (circRNAs) in the oncogenesis and metastasis of various cancers. We previously reported that circACTN4 could bind with FUBP1 to promote tumorigenesis and the development of breast cancer (BC) by increasing the expression of MYC. However, its exact molecular mechanism and biological function have not been fully elucidated. Methods: Here, Circular RNA microarray analysis was conducted in 3 pairs of BC and paracancerous tissues. The expression of circACTN4 in BC cells and tissues was detected via reverse transcription‒quantitative PCR (RT‒qPCR). Cell Counting Kit-8 (CCK-8), 5-ethynyl-2-deoxyuridine… More > Graphic Abstract

YONGFENG CHENG¹, YIPING SHEN², YUNFEI ZHANG¹, HAILIQIGULI NURIDING¹, XUEMEI WANG¹, CHUNYAN FAN¹, GULIBAHA MAIMAITI¹, YU LIU¹, YINGBIN YUE¹, DANLU LI¹, MEI YAN^1,*

Oncology Research, Vol.33, No.5, pp. 1173-1187, 2025, DOI:10.32604/or.2025.057842 - 18 April 2025

Abstract Background: The growth of the B-cell lymphoma subtype, Hodgkin lymphoma (HL), is associated with increased autophagy. A mycobacterial antigen, Ag85, has been reported to inhibit cell autophagy under a variety of conditions. Whether Ag85 could inhibit autophagy in HL is unknown. Methods: Lymph node samples from patients with HL and healthy controls were collected to assess proliferation and autophagy. The human HL cell line, L-428, was cultured and subjected to Ag85B treatment. Autophagy in L-428 cells was evaluated through western blotting analysis, immunohistochemistry, and transmission electron microscopy. Apoptosis in these cells was measured using flow… More >