Ghadah Naif Alwakid1, Samabia Tehsin2,*, Mamoona Humayun3,*, Asad Farooq2, Ibrahim Alrashdi1, Amjad Alsirhani1
CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-21, 2026, DOI:10.32604/cmc.2025.069162
- 10 November 2025
Abstract Skin diseases affect millions worldwide. Early detection is key to preventing disfigurement, lifelong disability, or death. Dermoscopic images acquired in primary-care settings show high intra-class visual similarity and severe class imbalance, and occasional imaging artifacts can create ambiguity for state-of-the-art convolutional neural networks (CNNs). We frame skin lesion recognition as graph-based reasoning and, to ensure fair evaluation and avoid data leakage, adopt a strict lesion-level partitioning strategy. Each image is first over-segmented using SLIC (Simple Linear Iterative Clustering) to produce perceptually homogeneous superpixels. These superpixels form the nodes of a region-adjacency graph whose edges encode… More >