Peihe Wang*, Yuanyuan Cai*, Dongju Lin†, Yingxiao Jiang*
Oncology Research, Vol.25, No.7, pp. 1199-1205, 2017, DOI:10.3727/096504017X14873444858101
Abstract Gamma ray can promote cancer cell apoptosis and cell cycle arrest. It is often used in the clinical treatment of
tumors, including lung cancer. In this study, we aimed to explore the role of gamma ray treatment and its correlation with BTG2 in cell proliferation, apoptosis, and cell cycle arrest regulation in a lung cancer cell line.
A549 cell viability, apoptosis rate, and cell cycle were investigated after gamma ray treatment. We then used
siRNA for BTG2 to detect the effect of BTG2 knockdown on the progress of gamma ray-treated lung cancer
cells. Finally, we… More >
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