Pengwei Lu, Yuanting Gu, Lin Li, Fang Wang, Xue Yang, Yunqing Yang
Oncology Research, Vol.26, No.4, pp. 625-635, 2018, DOI:10.3727/096504017X14953948675395
Abstract Breast cancer is a serious threat to women’s physical and psychological health. Long noncoding RNA CAMTA1
(lncCAMTA1) was believed to be related with tumor progression, but its role in breast cancer is not clear.
The human breast cancer cell line MDA-MB-231 was used to investigate the effect of lncCAMTA1 on cell
viability, migration/invasion, and apoptosis. The expression of lncCAMTA1, miR-20b, and VEGF in MDAMB-231 were measured after corresponding transfections. Binding effects between lncCAMTA1 and miR-20b,
miR-20b, and VEGF 3'-UTR were measured. The effects of miR-20b and VEGF on breast cancer cells were
also assessed after… More >
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