Chunsheng Li*, Jingrong Dong†, Zhenqi Han†, Kai Zhang‡
Oncology Research, Vol.25, No.4, pp. 617-627, 2017, DOI:10.3727/096504016X14768374457986
Abstract MicroRNAs (miRNAs) are reportedly involved in gastric cancer development and progression. In particular,
miR-219-5p has been reported to be a tumor-associated miRNA in human cancer. However, the role of miR-
219-5p in gastric cancer remains unclear. In this study, we investigated for the first time the potential role and
underlying mechanism of miR-219-5p in the proliferation, migration, and invasion of human gastric cancer
cells. miR-219-5p was found to be markedly decreased in gastric cancer tissues and cell lines compared with
adjacent tissues and normal gastric epithelial cells. miR-219-5p mimics or anti-miR-219-5p was transfected
into gastric… More >
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