Junfeng Zhang*1, Kun Xu†1, Lili Shi*, Li Zhang*, Zhaohua Zhao*, Hao Xu*, Fei Liang*, Hongbo Li*, Yan Zhao*, Xi Xu*, Yingfang Tian‡
Oncology Research, Vol.25, No.8, pp. 1317-1327, 2017, DOI:10.3727/096504017X14874323871217
Abstract Increasing studies have suggested that microRNAs (miRNAs) are involved in the development of gliomas.
MicroRNA-216a has been reported to be a tumor-associated miRNA in many types of cancer, either as an
oncogene or as a tumor suppressor. However, little is known about the function of miR-216a in gliomas. The
present study was designed to explore the potential role of miR-216a in gliomas. We found that miR-216a was
significantly decreased in glioma tissues and cell lines. Overexpression of miR-216a significantly suppressed
the proliferation, migration, and invasion of glioma cells. Leucine-rich repeat-containing G protein-coupled
receptor 5 (LGR5) More >
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