Fuqiang Wan*, Li Peng*, ChaoYu Zhu†, XinFa Zhang‡, FangWen Chen*, Tao Liu§
Oncology Research, Vol.25, No.4, pp. 503-510, 2017, DOI:10.3727/096504016X14755368915591
Abstract Latent transforming growth factor-b (TGF-b)-binding protein 2 (LTBP2) is one of four proteins in the LTBP
family of proteins (LTBP1–4) and was shown to play a vital role in tumorigenesis. However, little is known
regarding the functional role of LTBP2 in thyroid carcinoma. Therefore, the current study aimed to evaluate
the effect of LTBP2 expression on the proliferation, invasion, and tumorigenesis in thyroid carcinoma cells
and to explore the molecular mechanism of LTBP2 in tumor progression. Our results showed that the expression of LTBP2 is upregulated in human thyroid carcinoma and cell lines. Knockdown of More >
Login
Register
