Dorota Mańkowska-Wierzbicka, Ewelina Swora-Cwynar, Barbara Poniedziałek, Zygmunt Adamski, Agnieszka Dobrowolska, Jacek Karczewski
European Cytokine Network, Vol.26, No.2, pp. 26-37, 2015, DOI:10.1684/ecn.2015.0363
Abstract Introduction: This study aimed to compare the accuracy of selected laboratory markers in assessing
disease activity in patients with ulcerative colitis (UC). The analysis included serum IL-2, IL-4, IL-6, IL-10, IL-17,
TNF-α, IFN-γ, hsCRP, peripheral regulatory T cells, as well as fecal calprotectin and lactoferrin. Patients and
methods: A group of 45 adults with UC was enrolled in the study. Disease activity was assessed using the Mayo
endoscopic index, while for clinical activity scoring, the Clinical Activity Index (CAI) was used. Concentrations of
markers investigated were estimated by means of flow cytometry and enzyme-linked immunosorbent… More >
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