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  • Open Access

    SHORT COMMUNICATION

    New Definitions of the Isometric Latitude and the Mercator Projection

    Miljenko Lapaine*

    Revue Internationale de Géomatique, Vol.33, pp. 155-165, 2024, DOI:10.32604/rig.2024.052258 - 10 June 2024

    Abstract The short communication discusses the interrelationships of loxodromes, isometric latitudes and the normal aspect of Mercator projection. It is shown that by applying the isometric latitude, a very simple equation of the loxodrome on the sphere is reached. The consequence of this is that the isometric latitude can be defined using the generalized longitude, and not only using the latitude, as was common until now. Generalized longitude is the longitude defined for every real number; modulo 2π of generalized and usual longitude are congruent. Since the image of the loxodrome in the plane of the… More > Graphic Abstract

    New Definitions of the Isometric Latitude and the Mercator Projection

  • Open Access

    ARTICLE

    Highly Differentiated Target Detection under Extremely Low-Light Conditions Based on Improved YOLOX Model

    Haijian Shao1,2,*, Suqin Lei1, Chenxu Yan3, Xing Deng1, Yunsong Qi1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1507-1537, 2024, DOI:10.32604/cmes.2024.050140 - 20 May 2024

    Abstract This paper expounds upon a novel target detection methodology distinguished by its elevated discriminatory efficacy, specifically tailored for environments characterized by markedly low luminance levels. Conventional methodologies struggle with the challenges posed by luminosity fluctuations, especially in settings characterized by diminished radiance, further exacerbated by the utilization of suboptimal imaging instrumentation. The envisioned approach mandates a departure from the conventional YOLOX model, which exhibits inadequacies in mitigating these challenges. To enhance the efficacy of this approach in low-light conditions, the dehazing algorithm undergoes refinement, effecting a discerning regulation of the transmission rate at the pixel… More > Graphic Abstract

    Highly Differentiated Target Detection under Extremely Low-Light Conditions Based on Improved YOLOX Model

  • Open Access

    ARTICLE

    Fabrication of UV–Curing Linalool–Polysiloxane Hybrid Films with High Refractive Index and Transparency

    Wenqing Xiao1,#, Lewen Tan1,2,#, Xunjun Chen1,*, Qiaoguang Li1,*, Yunqing Ruan1

    Journal of Renewable Materials, Vol.12, No.3, pp. 569-583, 2024, DOI:10.32604/jrm.2023.046662 - 11 April 2024

    Abstract

    In this article, a series of high refractive indices (1.50–1.53) thiol phenyl polysiloxane (TPS) were synthesized via hydrolytic sol–gel reaction. The Fourier transform infrared spectra (FT–IR) and nuclear magnetic resonance spectra (NMR) results showed that TPS conformed to the predicted structures. Natural terpene linalool was exploited as photocrosslinker to fabricate UV–curing linalool–polysiloxane hybrid films (LPH) with TPS via photoinitiated thiol–ene reaction. LPH rapidly cured under UV irradiation at the intensity of 80 mW/cm2 in 30 s, exhibiting good UV–curing properties. The optical transmittance of LPH in the wavelength of 300–800 nm was over 90%, exhibiting good

    More >

  • Open Access

    ARTICLE

    Neural Wiskott-Aldrich syndrome protein (N-WASP) promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2

    HYUNG SUN KIM1,#, YUN SUN LEE2,#, SEUNG MYUNG DONG3, HYO JUNG KIM1, DA EUN LEE2, HYEON WOONG KANG2, MYEONG JIN KIM2, JOON SEONG PARK1,*

    Oncology Research, Vol.32, No.4, pp. 615-624, 2024, DOI:10.32604/or.2024.044029 - 20 March 2024

    Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid malignancies. A specific mechanism of its metastasis has not been established. In this study, we investigated whether Neural Wiskott-Aldrich syndrome protein (N-WASP) plays a role in distant metastasis of PDAC. We found that N-WASP is markedly expressed in clinical patients with PDAC. Clinical analysis showed a notably more distant metastatic pattern in the N-WASP-high group compared to the N-WASP-low group. N-WASP was noted to be a novel mediator of epithelial-mesenchymal transition (EMT) via gene expression profile studies. Knockdown of N-WASP in pancreatic cancer cells… More > Graphic Abstract

    Neural Wiskott-Aldrich syndrome protein (N-WASP) promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2

  • Open Access

    ARTICLE

    Target Detection Algorithm in Foggy Scenes Based on Dual Subnets

    Yuecheng Yu1,*, Liming Cai1, Anqi Ning1, Jinlong Shi1, Xudong Chen2, Shixin Huang1

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1915-1931, 2024, DOI:10.32604/cmc.2024.046125 - 27 February 2024

    Abstract Under the influence of air humidity, dust, aerosols, etc., in real scenes, haze presents an uneven state. In this way, the image quality and contrast will decrease. In this case, It is difficult to detect the target in the image by the universal detection network. Thus, a dual subnet based on multi-task collaborative training (DSMCT) is proposed in this paper. Firstly, in the training phase, the Gated Context Aggregation Network (GCANet) is used as the supervisory network of YOLOX to promote the extraction of clean information in foggy scenes. In the test phase, only the… More >

  • Open Access

    ARTICLE

    Multi-Equipment Detection Method for Distribution Lines Based on Improved YOLOx-s

    Lei Hu1,*, Yuanwen Lu1, Si Wang2, Wenbin Wang3, Yongmei Zhang4

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2735-2749, 2023, DOI:10.32604/cmc.2023.042974 - 26 December 2023

    Abstract The YOLOx-s network does not sufficiently meet the accuracy demand of equipment detection in the autonomous inspection of distribution lines by Unmanned Aerial Vehicle (UAV) due to the complex background of distribution lines, variable morphology of equipment, and large differences in equipment sizes. Therefore, aiming at the difficult detection of power equipment in UAV inspection images, we propose a multi-equipment detection method for inspection of distribution lines based on the YOLOx-s. Based on the YOLOx-s network, we make the following improvements: 1) The Receptive Field Block (RFB) module is added after the shallow feature layer… More >

  • Open Access

    ARTICLE

    Pre-Locator Incorporating Swin-Transformer Refined Classifier for Traffic Sign Recognition

    Qiang Luo1, Wenbin Zheng1,2,*

    Intelligent Automation & Soft Computing, Vol.37, No.2, pp. 2227-2246, 2023, DOI:10.32604/iasc.2023.040195 - 21 June 2023

    Abstract In the field of traffic sign recognition, traffic signs usually occupy very small areas in the input image. Most object detection algorithms directly reduce the original image to a specific size for the input model during the detection process, which leads to the loss of small object information. Additionally, classification tasks are more sensitive to information loss than localization tasks. This paper proposes a novel traffic sign recognition approach, in which a lightweight pre-locator network and a refined classification network are incorporated. The pre-locator network locates the sub-regions of the traffic signs from the original… More >

  • Open Access

    ARTICLE

    Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect

    OMER ERDOGAN1, GULEN MELIKE DEMIRBOLAT2, OZGE CEVIK1,*

    BIOCELL, Vol.47, No.5, pp. 1051-1063, 2023, DOI:10.32604/biocell.2023.028129 - 10 April 2023

    Abstract Background: Raloxifene, a selective estrogen receptor modulator, is also known to be a lysosomotropic agent. The bioavailability of raloxifene is around 2% due to extensive hepatic transport. Exosomes are nanosized vesicles that are naturally released from cells. Method: In this study, exosomes released from HeLa cervical cancer cells were loaded with raloxifene to increase its bioavailability, and an aptamer was attached to the exosome membrane for targeting only HeLa cells. Characterization of exosomes isolated from HeLa cells was performed by transmission electron microscopy, zeta sizer, and western blotting. In addition, the cytotoxic, apoptotic, autophagic, and lysosomotropic More >

  • Open Access

    ARTICLE

    The antioxidant trolox inhibits aging and enhances prostaglandin E-2 secretion in mesenchymal stem cells

    XIAOXU ZHANG1,2, LIN ZHANG1, LIN DU3, HUIYAN SUN4, XIA ZHAO2, YANG SUN1, WEI WANG2,*, LISHENG WANG1,3,*

    BIOCELL, Vol.47, No.2, pp. 385-392, 2023, DOI:10.32604/biocell.2023.025203 - 18 November 2022

    Abstract Mesenchymal stem cells (MSCs) have been widely used in regenerative medicine and clinical therapy due to their capabilities of proliferation, differentiation, and immune regulation. However, during in vitro expansion, MSCs are prone to aging, which largely limits their application. Prostaglandin E-2 (PGE-2) is a key effector secreted by MSCs to exert immunomodulatory effects. By screening the compound library for PGE-2 secretion, the antioxidant trolox was verified as a stimulator of MSCs to secrete PGE-2. The effect of antioxidant trolox on biological characteristics of MSCS, including aging, proliferation, and gene expression, was examined. The results demonstrated that More >

  • Open Access

    ARTICLE

    Hyperbaric oxygen protects against PC12 and H9C2 cell damage caused by oxygen–glucose deprivation/reperfusion via the inhibition of cell apoptosis and autophagy

    JIANRONG YANG1,#, WAN CHEN2,#, XING ZHOU3,#, YAOXUAN LI4,#, ZHIHUANG NONG5, LIYUAN ZHOU4, XUAN WEI4, XIAORONG PAN6, CHUNXIA CHEN7, WENSHENG LU3

    BIOCELL, Vol.46, No.1, pp. 137-148, 2022, DOI:10.32604/biocell.2022.016807 - 28 September 2021

    Abstract In this study, we investigated the protective effect of hyperbaric oxygen (HBO) on PC12 and H9C2 cell damage caused by oxygen-glucose deprivation/reperfusion and its possible mechanism. PC12 and H9C2 cell oxygen-glucose deprivation/reperfusion model were established. Cells were divided into a control group, model group, hyperbaric air (HBA) group and HBO group. The cell viability was detected by the CCK8 assay. Hoechst 33342 and PI staining assays and mitochondrial membrane potential (MMP) assays were used to detect cell apoptosis. The ultrastructure of cells, including autophagosomes, lysosomes, and apoptosis, were examined using a transmission electron microscope. The… More >

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