Hai-Feng Zeng*, Hai-Yan Qiu†, Fa-Bo Feng‡
Oncology Research, Vol.26, No.3, pp. 335-343, 2018, DOI:10.3727/096504017X14907375885605
Abstract Long noncoding RNAs (lncRNAs) have been verified to participate in various types of malignant tumors,
including osteosarcoma (OS), which is the most common primary bone tumor with outstanding morbidity.
Although an increasing number of lncRNAs have been reported to mediate the occurrence of OS, the potential
mechanisms are still unclear. This study intends to uncover the mechanism by which lncRNA LINC01133
functions as an miRNA sponge to mediate OS tumorigenicity. In this study, we found that the expression level
of LINC01133 was statistically upregulated in OS tumor tissue and cell lines compared to noncancerous tissues More >