Hai-Tao Li, Dao-Yong Dong, Qiang Liu, Yi-Qin Xu, Langbo Chen
Oncology Research, Vol.27, No.4, pp. 423-429, 2019, DOI:10.3727/096504017X15030178624579
Abstract LACTB, a mitochondrial protein, was ubiquitously expressed in different mammalian tissues, such as liver,
heart, and skeletal muscle. It has been shown that LACTB is downexpressed in breast cancers, and it suppresses the proliferation and promotes the apoptosis of breast cancers. However, its role in the progression
and prognosis of glioma remains unknown. In this study, we analyzed the clinicopathological features and
outcomes of LACTB expression in 98 glioma patients and investigated the effects of LACTB overexpression
on the proliferation, invasion, and angiogenesis of glioma cells in vitro. We observed a significant decrease in
LACTB More >
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