Samaneh Kouzegaran*, Kourosh Shahraki†, Ali Makateb‡, Farkhondeh Shahri§, Negin Hatami¶, Vahid Behnod#, Amir Saber Tanha**
Oncology Research, Vol.25, No.4, pp. 471-478, 2017, DOI:10.3727/096504016X14721217330657
Abstract In this study, expression of FasL and Ki-67 messenger RNA (FasL and Ki-67 mRNA) in human retinoblastoma (HRB) was examined by the immunohistochemistry method and quantitative real-time PCR. Positive
expression of Ki-67 in tumor cells was detected in 16 of 30 patients (53.33%), and only 9 (30%) of the tissues
from patients with retinoblastoma showed positive staining for FasL. Our results revealed that FasL expression was significantly higher in tumor tissue with invasion compared with the noninvasion form (p = 0.033).
Ki-67 expression was markedly increased in tumor tissues with invasion compared with the noninvasion group… More >
Login
Register
