Ruihan Zhang1,2, Junhao Yang1, Chunxiao Chen1,*
Molecular & Cellular Biomechanics, Vol.15, No.3, pp. 177-187, 2018, DOI:10.3970/mcb.2018.04292
Abstract The proportion of cells staining for the nuclear antigen Ki-67 is an important predictive indicator for assessment of tumor cell proliferation and growth in routine pathological investigation. Instead of traditional scoring methods based on the experience of a trained laboratory scientist, deep learning approach can be automatically used to analyze the expression of Ki-67 as well. Deep learning based on convolutional neural networks (CNN) for image classification and single shot multibox detector (SSD) for object detection are used to investigate the expression of Ki-67 for assessment of biopsies from patients with breast cancer in this More >
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