YONGLI WANG1,2,#, SHENHONG QU2,#, YONG YANG1, YING QIN2, FEI LIU3, GUANGWU HUANG1,*
BIOCELL, Vol.47, No.3, pp. 533-545, 2023, DOI:10.32604/biocell.2023.025280
Abstract Background: Kinesin family member 15 (KIF15) is a protein that regulates cell mitosis and plays an important
role in the development and progression of several types of human cancers. However, the role of KIF15 in the
development of nasopharyngeal cancer (NPC) is still unclear. Methods: The differential expression of KIF15 in NPC
and para-carcinoma tissues was evaluated based on data collected from Gene Expression Omnibus (GEO) database
and immunohistochemical analysis of clinical specimens collected from a patient cohort. Cell lines 5-8F and CNE-2Z
were selected for the construction of KIF15‑knockdown cell models. CCK8 assay, flow cytometry, wound healing,
Transwell and… More >
Login
Register
