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  • Open Access

    ARTICLE

    A New Approach for Evaluating and Optimizing Hydraulic Fracturing in Coalbed Methane Reservoirs

    Xia Yan1, Wei Wang1, Kai Shen2,*, Yanqing Feng1, Junyi Sun1, Xiaogang Li1, Wentao Zhu1, Binbin Shi1, Guanglong Sheng2,3

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.070360 - 27 December 2025

    Abstract In the development of coalbed methane (CBM) reservoirs using multistage fractured horizontal wells, there often exist areas that are either repeatedly stimulated or completely unstimulated between fracturing stages, leading to suboptimal reservoir performance. Currently, there is no well-established method for accurately evaluating the effectiveness of such stimulation. This study introduces, for the first time, the concept of the Fracture Network Bridging Coefficient (FNBC) as a novel metric to assess stimulation performance. By quantitatively coupling the proportions of unstimulated and overstimulated volumes, the FNBC effectively characterizes the connectivity and efficiency of the fracture network. A background… More >

  • Open Access

    ARTICLE

    Learning Time Embedding for Temporal Knowledge Graph Completion

    Jinglu Chen1, Mengpan Chen2, Wenhao Zhang2,*, Huihui Ren2, Daniel Dajun Zeng1,2

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-25, 2026, DOI:10.32604/cmc.2025.069331 - 09 December 2025

    Abstract Temporal knowledge graph completion (TKGC), which merges temporal information into traditional static knowledge graph completion (SKGC), has garnered increasing attention recently. Among numerous emerging approaches, translation-based embedding models constitute a prominent approach in TKGC research. However, existing translation-based methods typically incorporate timestamps into entities or relations, rather than utilizing them independently. This practice fails to fully exploit the rich semantics inherent in temporal information, thereby weakening the expressive capability of models. To address this limitation, we propose embedding timestamps, like entities and relations, in one or more dedicated semantic spaces. After projecting all embeddings into… More >

  • Open Access

    ARTICLE

    AT-Net: A Semi-Supervised Framework for Asparagus Pathogenic Spore Detection under Complex Backgrounds

    Jiajun Sun, Shunshun Ji, Chao Zhang*

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.068668 - 09 December 2025

    Abstract Asparagus stem blight is a devastating crop disease, and the early detection of its pathogenic spores is essential for effective disease control and prevention. However, spore detection is still hindered by complex backgrounds, small target sizes, and high annotation costs, which limit its practical application and widespread adoption. To address these issues, a semi-supervised spore detection framework is proposed for use under complex background conditions. Firstly, a difficulty perception scoring function is designed to quantify the detection difficulty of each image region. For regions with higher difficulty scores, a masking strategy is applied, while the… More >

  • Open Access

    ARTICLE

    Bird Species Classification Using Image Background Removal for Data Augmentation

    Yu-Xiang Zhao*, Yi Lee

    CMC-Computers, Materials & Continua, Vol.84, No.1, pp. 791-810, 2025, DOI:10.32604/cmc.2025.065048 - 09 June 2025

    Abstract Bird species classification is not only a challenging topic in artificial intelligence but also a domain closely related to environmental protection and ecological research. Additionally, performing edge computing on low-level devices using small neural networks can be an important research direction. In this paper, we use the EfficientNetV2B0 model for bird species classification, applying transfer learning on a dataset of 525 bird species. We also employ the BiRefNet model to remove backgrounds from images in the training set. The generated background-removed images are mixed with the original training set as a form of data augmentation.… More >

  • Open Access

    ARTICLE

    Exploring the correlation and mechanism of natural killer cell cytotoxic sensitivity against gastric cancer

    WENZHUO YANG1,#, HAODONG CHEN2,#, ZHILAN ZHANG3, ZHIYONG XIA3, YUANYUAN JIN1,*, ZHAOYONG YANG1,*

    Oncology Research, Vol.33, No.6, pp. 1485-1494, 2025, DOI:10.32604/or.2025.059426 - 29 May 2025

    Abstract Background: Human natural killer (NK) cells have attracted widespread attention as a potential adoptive cell therapy (ACT). However, the therapeutic effects of NK cell infusion in patients with solid tumors are limited. There is an urgent need to explore a suitable new treatment plan to overcome weaknesses and support the superior therapeutic activity of NK cells. Methods: In this study, the mechanisms underlying the susceptibility of gastric cancer (GC) cell lines AGS, HGC-27, and NCI-N87 to NK cell-mediated cytotoxicity were explored. Results: Lactic dehydrogenase (LDH) release assays showed that all three GC cell lines were susceptible… More >

  • Open Access

    ARTICLE

    The alternatively spliced diacylglycerol kinase gamma-Δ exon13 transcript generated under hypoxia promotes glioblastoma progression

    MING YANG1,#, LIANGZHAO CHU1,#, SHUKAI LIN2, HAN PENG1, NIYA LONG1, KAYA XU1, HUA YANG1, FENG HAN1,*, JIAN LIU1,*

    Oncology Research, Vol.33, No.5, pp. 1189-1198, 2025, DOI:10.32604/or.2024.055102 - 18 April 2025

    Abstract Background: Glioblastoma (GBM) is one of the most malignant types of central nervous system tumors. Oxygen deprivation in the tumor microenvironment is thought to be an important factor in promoting GBM progression. However, the mechanisms of hypoxia-promoted tumor progression remain elusive. Methods: Alternative splicing of diacylglycerol kinase gamma (DGKG)-Δ exon13 was amplified and verified by PCR-Sanger sequencing. The functions of DGKG and DGKG-Δ exon13 were analyzed by Cell counting kit-8 (CCK-8), Transwell, Matrigel-transwell experiments, and in vivo orthotropic GBM animal models. Transcriptome analyses were done to find out the regulated genes. Results: In this study, we found… More > Graphic Abstract

    The alternatively spliced diacylglycerol kinase gamma-Δ exon13 transcript generated under hypoxia promotes glioblastoma progression

  • Open Access

    ARTICLE

    Exogenous Alpha-Ketoglutarate (AKG) Modulate Physiological Characteristics, Photosynthesis, Secondary Metabolism and Antioxidant Defense System in Peganum Harmala L. under Nickel Stress

    Marwa Rezgui1,#,*, Wided Ben Ammar1, Muhammad Nazim2,3,#, Walid Soufan4, Chiraz Chaffei Haouari1

    Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 137-155, 2025, DOI:10.32604/phyton.2025.058851 - 24 January 2025

    Abstract Nickel (Ni) toxicity significantly impairs plant growth, photosynthesis, and metabolism by inducing oxidative stress. This study evaluates the potential of exogenous Alpha-Ketoglutarate (AKG) in mitigating Ni-induced stress in Peganum harmala L. Seedlings were exposed to 0, 200, 500, and 750 μM NiCl2, with or without AKG supplementation. Under 750 μM Ni stress, dry weight (DW) decreased by 33.7%, tissue water content (TWC) by 39.9%, and chlorophyll a and total chlorophyll levels were reduced by 17% and 15%, respectively. Ni exposure also significantly increased secondary metabolite production, with leaf anthocyanin content rising by 131%, and superoxide dismutase (SOD)… More >

  • Open Access

    ARTICLE

    An Improved YOLOv8-Based Method for Real-Time Detection of Harmful Tea Leaves in Complex Backgrounds

    Xin Leng#, Jiakai Chen#, Jianping Huang*, Lei Zhang, Zongxuan Li

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2963-2981, 2024, DOI:10.32604/phyton.2024.057166 - 30 November 2024

    Abstract Tea, a globally cultivated crop renowned for its unique flavor profile and health-promoting properties, ranks among the most favored functional beverages worldwide. However, diseases severely jeopardize the production and quality of tea leaves, leading to significant economic losses. While early and accurate identification coupled with the removal of infected leaves can mitigate widespread infection, manual leaves removal remains time-consuming and expensive. Utilizing robots for pruning can significantly enhance efficiency and reduce costs. However, the accuracy of object detection directly impacts the overall efficiency of pruning robots. In complex tea plantation environments, complex image backgrounds, the… More >

  • Open Access

    ARTICLE

    Rapid Parameter-Optimizing Strategy for Plug-and-Play Devices in DC Distribution Systems under the Background of Digital Transformation

    Zhi Li1, Yufei Zhao2, Yueming Ji2, Hanwen Gu2, Zaibin Jiao2,*

    Energy Engineering, Vol.121, No.12, pp. 3899-3927, 2024, DOI:10.32604/ee.2024.055899 - 22 November 2024

    Abstract By integrating advanced digital technologies such as cloud computing and the Internet of Things in sensor measurement, information communication, and other fields, the digital DC distribution network can efficiently and reliably access Distributed Generator (DG) and Energy Storage Systems (ESS), exhibiting significant advantages in terms of controllability and meeting requirements of Plug-and-Play (PnP) operations. However, during device plug-in and -out processes, improper system parameters may lead to small-signal stability issues. Therefore, before executing PnP operations, conducting stability analysis and adjusting parameters swiftly is crucial. This study introduces a four-stage strategy for parameter optimization to enhance… More >

  • Open Access

    ARTICLE

    KGTLIR: An Air Target Intention Recognition Model Based on Knowledge Graph and Deep Learning

    Bo Cao1,*, Qinghua Xing2, Longyue Li2, Huaixi Xing1, Zhanfu Song1

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 1251-1275, 2024, DOI:10.32604/cmc.2024.052842 - 18 July 2024

    Abstract As a core part of battlefield situational awareness, air target intention recognition plays an important role in modern air operations. Aiming at the problems of insufficient feature extraction and misclassification in intention recognition, this paper designs an air target intention recognition method (KGTLIR) based on Knowledge Graph and Deep Learning. Firstly, the intention recognition model based on Deep Learning is constructed to mine the temporal relationship of intention features using dilated causal convolution and the spatial relationship of intention features using a graph attention mechanism. Meanwhile, the accuracy, recall, and F1-score after iteration are introduced More >

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