Perez Joan¹, Fusco Giovanni¹, Sadahiro Yukio²

Revue Internationale de Géomatique, Vol.31, No.2, pp. 303-327, 2022, DOI:10.3166/RIG.31.303-327© 2022

Abstract This paper presents different methods implemented with the aim of studying urban dynamics at the building level. Building types are identified within a comprehensive vector-based building inventory, spanning over at least two time points. First, basic morphometric indicators are computed for each building: area, floor-area, number of neighbors, elongation, and convexity. Based on the availability of expert knowledge, different types of classification and clustering are performed: supervised tree-like classificatory model, expert-constrained k-means and combined SOM-HCA. A grid is superimposed on the test region of Osaka (Japan) and the number of building types per cell and for each period is computed,… More >

MENNA AL-ADL^1,*, MAGDY M. YOUSSEF¹, AHMED EL-SEBAIE², SHERIF REFAAT³, AFAF EL-SAID⁴

Oncology Research, Vol.32, No.4, pp. 785-797, 2024, DOI:10.32604/or.2024.047021

Abstract Cytochromes P450 (CYPs) play a prominent role in catalyzing phase I xenobiotic biotransformation and account for about 75% of the total metabolism of commercially available drugs, including chemotherapeutics. The gene expression and enzyme activity of CYPs are variable between individuals, which subsequently leads to different patterns of susceptibility to carcinogenesis by genotoxic xenobiotics, as well as differences in the efficacy and toxicity of clinically used drugs. This research aimed to examine the presence of the CYP2B6*9 polymorphism and its possible association with the incidence of B-CLL in Egyptian patients, as well as the clinical outcome after receiving cyclophosphamide chemotherapy. DNA… More > Graphic Abstract

HUAN HU^1,2,*, YUE HUANG¹, FANGZHOU LIU¹, QIAN WANG^1,2, YANZI YAO^3,*

BIOCELL, Vol.48, No.3, pp. 353-362, 2024, DOI:10.32604/biocell.2024.048311

Abstract Increasing life expectancy and an aging population lead to age-related bone diseases like osteoporosis and low bone mass more prevalent. These conditions represent a common, costly and chronic burden, not only for elderly but also to society at large. Consequently, elucidating the pathophysiology and developing effective therapies for these diseases is of paramount importance. Recent advances in research have identified the gut as a novel and promising target for addressing bone disorders, giving rise to the concept of the “gut-bone axis”. An in-depth review of the latest insights into the effects of age-related physiological changes in the gastrointestinal tract on… More >

Nazik Alturki¹, Raed Alharthi², Muhammad Umer^3,*, Oumaima Saidani¹, Amal Alshardan¹, Reemah M. Alhebshi⁴, Shtwai Alsubai⁵, Ali Kashif Bashir^6,7,8,*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3387-3415, 2024, DOI:10.32604/cmes.2023.044700

Abstract The concept of smart houses has grown in prominence in recent years. Major challenges linked to smart homes are identification theft, data safety, automated decision-making for IoT-based devices, and the security of the device itself. Current home automation systems try to address these issues but there is still an urgent need for a dependable and secure smart home solution that includes automatic decision-making systems and methodical features. This paper proposes a smart home system based on ensemble learning of random forest (RF) and convolutional neural networks (CNN) for programmed decision-making tasks, such as categorizing gadgets as “OFF” or “ON” based… More >

Ashraf S. Mashaleh^1,2,*, Noor Farizah Binti Ibrahim¹, Mohammad Alauthman³, Mohammad Almseidin⁴, Amjad Gawanmeh⁵

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2245-2267, 2024, DOI:10.32604/cmc.2023.047323

Abstract Increasing Internet of Things (IoT) device connectivity makes botnet attacks more dangerous, carrying catastrophic hazards. As IoT botnets evolve, their dynamic and multifaceted nature hampers conventional detection methods. This paper proposes a risk assessment framework based on fuzzy logic and Particle Swarm Optimization (PSO) to address the risks associated with IoT botnets. Fuzzy logic addresses IoT threat uncertainties and ambiguities methodically. Fuzzy component settings are optimized using PSO to improve accuracy. The methodology allows for more complex thinking by transitioning from binary to continuous assessment. Instead of expert inputs, PSO data-driven tunes rules and membership functions. This study presents a… More >

Xiao Feng^1,2,3,*, Zheng Yuan¹

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1881-1895, 2024, DOI:10.32604/cmc.2023.047243

Abstract First, we propose a cross-domain authentication architecture based on trust evaluation mechanism, including registration, certificate issuance, and cross-domain authentication processes. A direct trust evaluation mechanism based on the time decay factor is proposed, taking into account the influence of historical interaction records. We weight the time attenuation factor to each historical interaction record for updating and got the new historical record data. We refer to the beta distribution to enhance the flexibility and adaptability of the direct trust assessment model to better capture time trends in the historical record. Then we propose an autoencoder-based trust clustering algorithm. We perform feature… More >

Huixiang Xu^*

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2309-2335, 2024, DOI:10.32604/cmc.2024.046253

Abstract The Internet of Things (IoT) has revolutionized how we interact with and gather data from our surrounding environment. IoT devices with various sensors and actuators generate vast amounts of data that can be harnessed to derive valuable insights. The rapid proliferation of Internet of Things (IoT) devices has ushered in an era of unprecedented data generation and connectivity. These IoT devices, equipped with many sensors and actuators, continuously produce vast volumes of data. However, the conventional approach of transmitting all this data to centralized cloud infrastructures for processing and analysis poses significant challenges. However, transmitting all this data to a… More >

Ali Hamid Farea^1,*, Omar H. Alhazmi¹, Kerem Kucuk²

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1525-1545, 2024, DOI:10.32604/cmc.2023.045794

Abstract While emerging technologies such as the Internet of Things (IoT) have many benefits, they also pose considerable security challenges that require innovative solutions, including those based on artificial intelligence (AI), given that these techniques are increasingly being used by malicious actors to compromise IoT systems. Although an ample body of research focusing on conventional AI methods exists, there is a paucity of studies related to advanced statistical and optimization approaches aimed at enhancing security measures. To contribute to this nascent research stream, a novel AI-driven security system denoted as “AI2AI” is presented in this work. AI2AI employs AI techniques to… More >

DONGQIN WANG^1,4, YAN SHI¹, ZHIQIANG WANG⁴, JING ZHANG², LUYAO WANG², HONGYU MA³, SHUHUA SHI², XIAOFU LIAN², HUA HUANG⁴, XIAOJING WANG^1,*, CHAOQUN LIAN^4,*

BIOCELL, Vol.48, No.1, pp. 111-122, 2024, DOI:10.32604/biocell.2023.046903

Abstract Introduction: Among all malignant tumors of the digestive system, pancreatic carcinoma exhibits the highest mortality rate. Currently, prevention and effective treatment are urgent issues that need to be addressed. Methods: The study focused on meiotic nuclear divisions 1 (MND1), integrating data from the Gene Expression Profiling Interactive Analysis (GEPIA) database with prognostic survival analysis. Simultaneously, experiments at cellular level were employed to demonstrate the effect of MND1 on the proliferation and migration of PC. The small-molecule inhibitor of MND1 was used to suppress the migration of PC cells by knocking down MND1 using small interfering RNA (siRNA) in Patu-8988 and… More >

YU LIU^*, ROBERT J. KASPER, NATALIE J. S. CHOI^*

BIOCELL, Vol.48, No.1, pp. 1-8, 2024, DOI:10.32604/biocell.2023.031158

Abstract Extracellular vesicles (EVs) are membranous vesicular structures released from almost all eukaryotic cell types under different physiological or pathological conditions. Growing evidence demonstrates that EVs can serve as mediators of intercellular communication between donor and recipient cells or microorganism-infected and noninfected cells. Coronavirus disease 2019 (COVID-19) disease is caused by infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of host cells in the respiratory system and various extra-pulmonary tissue/organs, resulting in complications of multiple organ systems. As the cell surface receptor, angiotensin-converting enzyme 2 (ACE2) mediates cellular entry of SARS-CoV-2 into the host cells in patients with COVID-19.… More >