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  • Open Access

    ARTICLE

    Blade Wrap Angle Impact on Centrifugal Pump Performance: Entropy Generation and Fluid-Structure Interaction Analysis

    Hayder Kareem Sakran1,2, Mohd Sharizal Abdul Aziz1,*, Chu Yee Khor3

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 109-137, 2024, DOI:10.32604/cmes.2024.047245

    Abstract The centrifugal pump is a prevalent power equipment widely used in different engineering patterns, and the impeller blade wrap angle significantly impacts its performance. A numerical investigation was conducted to analyze the influence of the blade wrap angle on flow characteristics and energy distribution of a centrifugal pump evaluated as a low specific speed with a value of 69. This study investigates six impeller models that possess varying blade wrap angles (95°, 105°, 115°, 125°, 135°, and 145°) that were created while maintaining the same volute and other geometrical characteristics. The investigation of energy loss was conducted to evaluate the… More > Graphic Abstract

    Blade Wrap Angle Impact on Centrifugal Pump Performance: Entropy Generation and Fluid-Structure Interaction Analysis

  • Open Access

    ARTICLE

    Toughening of Unsaturated Polyester Resin by Blending with Polyether Telechelics. Dependency of Toughening Efficacy on End Groups

    JEEMOL. P. A1, SURESH MATHEW1, REGHUNADHAN NAIR C.P.2,*

    Journal of Polymer Materials, Vol.39, No.1-2, pp. 111-120, 2022, DOI:10.32381/JPM.2022.39.1-2.7

    Abstract Polyether telechelics based on ethylene glycol,1,2-propylene glycol and 1,4- butylene glycol of with various molar masses and bearing at both terminals functional groups such as maleimide, itaconimide, nadimide and hydroxyl groups were individually examined as toughening agents for an unsaturated polyester resin (UPER). For a given telechelic, the toughening effect was evaluated at different mass ratios. The difference in toughening efficacy arose from the differential reactivity of the telechelics end groups combined with the unsaturation of the UPER with the reactive diluent, styrene. This causes a differential distribution of the polyether groups in the UPER matrices, resulting in a differential… More >

  • Open Access

    ARTICLE

    Enhancing ChatGPT’s Querying Capability with Voice-Based Interaction and CNN-Based Impair Vision Detection Model

    Awais Ahmad1, Sohail Jabbar1,*, Sheeraz Akram1, Anand Paul2, Umar Raza3, Nuha Mohammed Alshuqayran1

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3129-3150, 2024, DOI:10.32604/cmc.2024.045385

    Abstract This paper presents an innovative approach to enhance the querying capability of ChatGPT, a conversational artificial intelligence model, by incorporating voice-based interaction and a convolutional neural network (CNN)-based impaired vision detection model. The proposed system aims to improve user experience and accessibility by allowing users to interact with ChatGPT using voice commands. Additionally, a CNN-based model is employed to detect impairments in user vision, enabling the system to adapt its responses and provide appropriate assistance. This research tackles head-on the challenges of user experience and inclusivity in artificial intelligence (AI). It underscores our commitment to overcoming these obstacles, making ChatGPT… More >

  • Open Access

    ARTICLE

    MICROCANTILEVERS IN BIOMEDICAL AND THERMO/FLUID APPLICATIONS

    Khalil Khanafera, Kambiz Vafaib,*

    Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-9, 2010, DOI:10.5098/hmt.v1.2.3004

    Abstract A study was conducted to demonstrate the applications of microcantilevers in biomedical and thermo/fluid fields. The deflection of the microcantilevers due to biomaterial and turbulence effects was highlighted in this work. The novel patented microcantilever assemblies that were presented in this study can increase the signal and decrease the unfavorable deflection due to flow disturbances. This work paves the road for researchers in the area microcantilever based biosensors to design efficient microsensor systems that exhibit minimal errors in the measurements. Fluid-structure interaction was also utilized to investigate some aspects of the fluid flow and heat transfer characteristics. More >

  • Open Access

    ARTICLE

    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation

    WEN GE1,2,#, YA LI1,2,#, YUTING RUAN1,2, NINGXIA WU1,2, PEI MA3,4, TONGPENG XU3,4, YONGQIAN SHU3,4, YINGWEI WANG1,2, WEN QIU1,2, CHENHUI ZHAO3,4,*

    Oncology Research, Vol.32, No.4, pp. 625-641, 2024, DOI:10.32604/or.2023.031053

    Abstract The cancer cell metastasis is a major death reason for patients with non-small cell lung cancer (NSCLC). Although researchers have disclosed that interleukin 17 (IL-17) can increase matrix metalloproteinases (MMPs) induction causing NSCLC cell metastasis, the underlying mechanism remains unclear. In the study, we found that IL-17 receptor A (IL-17RA), p300, p-STAT3, Ack-STAT3, and MMP19 were up-regulated both in NSCLC tissues and NSCLC cells stimulated with IL-17. p300, STAT3 and MMP19 overexpression or knockdown could raise or reduce IL-17-induced p-STAT3, Ack-STAT3 and MMP19 level as well as the cell migration and invasion. Mechanism investigation revealed that STAT3 and p300 bound… More > Graphic Abstract

    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation

  • Open Access

    ARTICLE

    Virtual Keyboard: A Real-Time Hand Gesture Recognition-Based Character Input System Using LSTM and Mediapipe Holistic

    Bijon Mallik1, Md Abdur Rahim1, Abu Saleh Musa Miah2, Keun Soo Yun3,*, Jungpil Shin2

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 555-570, 2024, DOI:10.32604/csse.2023.045981

    Abstract In the digital age, non-touch communication technologies are reshaping human-device interactions and raising security concerns. A major challenge in current technology is the misinterpretation of gestures by sensors and cameras, often caused by environmental factors. This issue has spurred the need for advanced data processing methods to achieve more accurate gesture recognition and predictions. Our study presents a novel virtual keyboard allowing character input via distinct hand gestures, focusing on two key aspects: hand gesture recognition and character input mechanisms. We developed a novel model with LSTM and fully connected layers for enhanced sequential data processing and hand gesture recognition.… More >

  • Open Access

    ARTICLE

    Detecting APT-Exploited Processes through Semantic Fusion and Interaction Prediction

    Bin Luo1,2,3, Liangguo Chen1,2,3, Shuhua Ruan1,2,3,*, Yonggang Luo2,3,*

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1731-1754, 2024, DOI:10.32604/cmc.2023.045739

    Abstract Considering the stealthiness and persistence of Advanced Persistent Threats (APTs), system audit logs are leveraged in recent studies to construct system entity interaction provenance graphs to unveil threats in a host. Rule-based provenance graph APT detection approaches require elaborate rules and cannot detect unknown attacks, and existing learning-based approaches are limited by the lack of available APT attack samples or generally only perform graph-level anomaly detection, which requires lots of manual efforts to locate attack entities. This paper proposes an APT-exploited process detection approach called ThreatSniffer, which constructs the benign provenance graph from attack-free audit logs, fits normal system entity… More >

  • Open Access

    REVIEW

    Autophagy and circadian rhythms: interactions and clinical implications

    TIANKAI DI1,2,#, ZHIFEI ZHOU3,#, FEN LIU4,#, YUJIANG CHEN5,*, LULU WANG1,*

    BIOCELL, Vol.48, No.1, pp. 33-45, 2024, DOI:10.32604/biocell.2023.031638

    Abstract Autophagy is a widespread biological process that controls cellular growth, survival, development, and death. Circadian rhythm is a recurring reaction of living organisms and behaviors to variations in surrounding brightness and obscurity. Most of the fundamental physiological processes in mammals, such as the sleep-wake pattern and the rhythm of nutrition and energy metabolism, are governed by circadian rhythms. Research has indicated that autophagy exhibits a specific circadian pattern in both normal and abnormal conditions. Autophagy can modulate circadian rhythms by breaking down proteins that regulate the circadian clock. The potential regulatory connection between the two has been a popular subject… More >

  • Open Access

    ARTICLE

    Interaction Mechanisms between Natural Debris Flow and Rigid Barrier Deflectors: A New Perspective for Rational Design and Optimal Arrangement

    Yu Huang1, Beilei Liu1, Dianlei Feng2,*, Hao Shi1

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1679-1699, 2024, DOI:10.32604/cmes.2023.044094

    Abstract Rigid barrier deflectors can effectively prevent overspilling landslides, and can satisfy disaster prevention requirements. However, the mechanisms of interaction between natural granular flow and rigid barrier deflectors require further investigation. To date, few studies have investigated the impact of deflectors on controlling viscous debris flows for geological disaster prevention. To investigate the effect of rigid barrier deflectors on impact mechanisms, a numerical model using the smoothed particle hydrodynamics (SPH) method with the Herschel–Bulkley model is proposed to simulate the interaction between natural viscous flow and single/dual barriers with and without deflectors. This model was validated using laboratory flume test data… More > Graphic Abstract

    Interaction Mechanisms between Natural Debris Flow and Rigid Barrier Deflectors: A New Perspective for Rational Design and Optimal Arrangement

  • Open Access

    ARTICLE

    An Intelligent MCGDM Model in Green Suppliers Selection Using Interactional Aggregation Operators for Interval-Valued Pythagorean Fuzzy Soft Sets

    Rana Muhammad Zulqarnain1, Wen-Xiu Ma1,2,3,*, Imran Siddique4, Hijaz Ahmad5,6, Sameh Askar7

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1829-1862, 2024, DOI:10.32604/cmes.2023.030687

    Abstract Green supplier selection is an important debate in green supply chain management (GSCM), attracting global attention from scholars, especially companies and policymakers. Companies frequently search for new ideas and strategies to assist them in realizing sustainable development. Because of the speculative character of human opinions, supplier selection frequently includes unreliable data, and the interval-valued Pythagorean fuzzy soft set (IVPFSS) provides an exceptional capacity to cope with excessive fuzziness, inconsistency, and inexactness through the decision-making procedure. The main goal of this study is to come up with new operational laws for interval-valued Pythagorean fuzzy soft numbers (IVPFSNs) and create two interaction… More >

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