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    REVIEW

    The Peritoneal Macrophages in Inflammatory Diseases and Abdominal Cancers

    Ting Liu1, Fang Liu1, Lei-Wen Peng, Li Chang, Yong-Mei Jiang

    Oncology Research, Vol.26, No.5, pp. 817-826, 2018, DOI:10.3727/096504017X15130753659625

    Abstract Peritoneal macrophages (PMs) are the major cell type of peritoneal cells that participate in multiple aspects of innate and acquired immunity in the peritoneal cavity. PMs have an ability to release a large amount of proinflammatory and anti-inflammatory cytokines and therefore play a critical role in regulating the differentiation of innate immune cells and inflammatory T cells. Accumulating studies demonstrate that the immunological reactions and inflammatory responses of PMs are strongly related to the pathogenic processes of various inflammatory diseases and abdominal cancers. Consequently, the regulation of PM activation has gradually emerged as a promising More >

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