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  • Open Access

    ARTICLE

    Shifting the Paradigm: A Fresh Look at Physical Activity Frequency and Its Impact on Mental Health, Life Satisfaction, and Self-Rated Health in Adolescents

    Wenjie Li1, Yucheng Gao2, Guoqing Liu2, Rongkai Hao2, Meijie Zhang2, Xiaotian Li1,*

    International Journal of Mental Health Promotion, Vol.26, No.2, pp. 83-92, 2024, DOI:10.32604/ijmhp.2023.042014

    Abstract As adolescent mental health problems are becoming a more serious issue globally, this paper explores the relationship of physical activity in adolescents and its frequency on mental health as well as examines the mediating effects of life satisfaction and self-rated health in order to provide a reference for the promotion of mental health in adolescents. A sample of 3578 Chinese high school students completed questionnaires assessing their mental health, physical activity frequency, life satisfaction, and self-rated health. The mean SCL-90 value for adolescents was found to be 1.629%, and 24.73% of adolescents had varying degrees of mental health issue. Increased… More >

  • Open Access

    ARTICLE

    Gastric cancer secreted miR-214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells

    WEIXUE WANG#, TONGTONG WANG#, YAN ZHANG, TING DENG, HAIYANG ZHANG*, YI BA*

    Oncology Research, Vol.32, No.3, pp. 489-502, 2024, DOI:10.32604/or.2023.046676

    Abstract Different from necrosis, apoptosis, autophagy and other forms of cell death, ferroptosis is a mechanism that catalyzes lipid peroxidation of polyunsaturated fatty acids under the action of iron divalent or lipoxygenase, leading to cell death. Apatinib is currently used in the third-line standard treatment of advanced gastric cancer, targeting the anti-angiogenesis pathway. However, Apatinib-mediated ferroptosis in vascular endothelial cells has not been reported yet. Tumor-secreted exosomes can be taken up into target cells to regulate tumor development, but the mechanism related to vascular endothelial cell ferroptosis has not yet been discovered. Here, we show that exosomes secreted by gastric cancer… More >

  • Open Access

    ARTICLE

    MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

    HUI SUN, MASANORI KAWANO*, TATSUYA IWASAKI, ICHIRO ITONAGA, YUTA KUBOTA, HIROSHI TSUMURA, KAZUHIRO TANAKA

    Oncology Research, Vol.32, No.3, pp. 463-476, 2024, DOI:10.32604/or.2023.044085

    Abstract An important factor in the emergence and progression of osteosarcoma (OS) is the dysregulated expression of microRNAs (miRNAs). Transcription factor 7-like 1 (TCF7L1), a member of the T cell factor/lymphoid enhancer factor (TCF/LEF) transcription factor family, interacts with the Wnt signaling pathway regulator β-catenin and acts as a DNA-specific binding protein. This study sought to elucidate the impact of the interaction between miR-329-3p and TCF7L1 on the growth and apoptosis of OS and analyze the regulatory expression relationship between miRNA and mRNA in osteosarcoma cells using a variety of approaches. MiR329-3p was significantly downregulated, while TCF7L1 was considerably up-regulated in… More > Graphic Abstract

    MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

  • Open Access

    ARTICLE

    Identification of Important FPGA Modules Based on Complex Network

    Senjie Zhang1,2, Jinbo Wang2,*, Shan Zhou2, Jingpei Wang2,3, Zhenyong Zhang4,*, Ruixue Wang2

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 1027-1047, 2024, DOI:10.32604/cmc.2023.046355

    Abstract The globalization of hardware designs and supply chains, as well as the integration of third-party intellectual property (IP) cores, has led to an increased focus from malicious attackers on computing hardware. However, existing defense or detection approaches often require additional circuitry to perform security verification, and are thus constrained by time and resource limitations. Considering the scale of actual engineering tasks and tight project schedules, it is usually difficult to implement designs for all modules in field programmable gate array (FPGA) circuits. Some studies have pointed out that the failure of key modules tends to cause greater damage to the… More >

  • Open Access

    ARTICLE

    Deep Learning-Based Classification of Rotten Fruits and Identification of Shelf Life

    S. Sofana Reka1, Ankita Bagelikar2, Prakash Venugopal2,*, V. Ravi2, Harimurugan Devarajan3

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 781-794, 2024, DOI:10.32604/cmc.2023.043369

    Abstract The freshness of fruits is considered to be one of the essential characteristics for consumers in determining their quality, flavor and nutritional value. The primary need for identifying rotten fruits is to ensure that only fresh and high-quality fruits are sold to consumers. The impact of rotten fruits can foster harmful bacteria, molds and other microorganisms that can cause food poisoning and other illnesses to the consumers. The overall purpose of the study is to classify rotten fruits, which can affect the taste, texture, and appearance of other fresh fruits, thereby reducing their shelf life. The agriculture and food industries… More >

  • Open Access

    ARTICLE

    Einstein Hybrid Structure of q-Rung Orthopair Fuzzy Soft Set and Its Application for Diagnosis of Waterborne Infectious Disease

    Rana Muhammad Zulqarnain1, Hafiz Khalil ur Rehman2, Imran Siddique3, Hijaz Ahmad4,5, Sameh Askar6, Shahid Hussain Gurmani1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1863-1892, 2024, DOI:10.32604/cmes.2023.031480

    Abstract This research is devoted to diagnosing water-borne infectious diseases caused by floods employing a novel diagnosis approach, the Einstein hybrid structure of q-rung orthopair fuzzy soft set. This approach integrates parts of fuzzy logic and soft set theory to develop a robust alternative for disease detection in stressful situations, especially in areas affected by floods. Compared to the traditional intuitionistic fuzzy soft set and Pythagorean fuzzy soft set, the q-rung orthopair fuzzy soft set (q-ROFSS) adequately incorporates unclear and indeterminate facts. The major objective of this investigation is to formulate the q-rung orthopair fuzzy soft Einstein hybrid weighted average (q-ROFSEHWA)… More >

  • Open Access

    ARTICLE

    Automatic SOC Equalization Strategy of Energy Storage Units with DC Microgrid Bus Voltage Support

    Jingjing Tian1, Shenglin Mo1,*, Feng Zhao1, Xiaoqiang Chen2

    Energy Engineering, Vol.121, No.2, pp. 439-459, 2024, DOI:10.32604/ee.2023.029956

    Abstract In this paper, an improved sag control strategy based on automatic SOC equalization is proposed to solve the problems of slow SOC equalization and excessive bus voltage fluctuation amplitude and offset caused by load and PV power variations in a stand-alone DC microgrid. The strategy includes primary and secondary control. Among them, the primary control suppresses the DC microgrid voltage fluctuation through the Ⅰ and Ⅱ section control, and the secondary control aims to correct the P-U curve of the energy storage system and the PV system, thus reducing the steady-state bus voltage excursion. The simulation results demonstrate that the… More >

  • Open Access

    ARTICLE

    Modeling of Large-Scale Hydrogen Storage System Considering Capacity Attenuation and Analysis of Its Efficiency Characteristics

    Junhui Li1, Haotian Zhang1, Cuiping Li1,*, Xingxu Zhu1, Ruitong Liu2, Fangwei Duan2, Yongming Peng3

    Energy Engineering, Vol.121, No.2, pp. 291-313, 2024, DOI:10.32604/ee.2023.027593

    Abstract In the existing power system with a large-scale hydrogen storage system, there are problems such as low efficiency of electric-hydrogen-electricity conversion and single modeling of the hydrogen storage system. In order to improve the hydrogen utilization rate of hydrogen storage system in the process of participating in the power grid operation, and speed up the process of electric-hydrogen-electricity conversion. This article provides a detailed introduction to the mathematical and electrical models of various components of the hydrogen storage unit, and also establishes a charging and discharging efficiency model that considers the temperature and internal gas partial pressure of the hydrogen… More >

  • Open Access

    ARTICLE

    Variation Characteristics of Root Traits of Different Alfalfa Cultivars under Saline-Alkaline Stress and their Relationship with Soil Environmental Factors

    Tian-Jiao Wei1, Guang Li1, Yan-Ru Cui1, Jiao Xie1, Xing-Ai Gao1, Xing Teng1, Xin-Ying Zhao1, Fa-Chun Guan1,*, Zheng-Wei Liang2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 29-43, 2024, DOI:10.32604/phyton.2023.046078

    Abstract Soil salinization is the main factor that threatens the growth and development of plants and limits the increase of yield. It is of great significance to study the key soil environmental factors affecting plant root traits to reveal the adaptation strategies of plants to saline-alkaline-stressed soil environments. In this study, the root biomass, root morphological parameters and root mineral nutrient content of two alfalfa cultivars with different sensitivities to alkaline stress were analyzed with black soil as the control group and the mixed saline-alkaline soil with a ratio of 7:3 between black soil and saline-alkaline soil as the saline-alkaline treatment… More >

  • Open Access

    ARTICLE

    The Effect of Soil Enzymes and Polysaccharides Secreted by the Roots of Salvia miltiorrhiza Bunge under Drought, High Temperature, and Nitrogen and Phosphorus Deficits

    Yong Qin1,2, Xiaoyu Li1,2, Yanhong Wu1,2, Hai Wang3, Guiqi Han1,2,3, Zhuyun Yan1,2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 119-135, 2024, DOI:10.32604/phyton.2023.046075

    Abstract Root exudates serve as crucial mediators for information exchange between plants and soil, and are an important evolutionary mechanism for plants’ adaptation to environmental changes. In this study, 15 different abiotic stress models were established using various stress factors, including drought (D), high temperature (T), nitrogen deficiency (N), phosphorus deficiency (P), and their combinations. We investigated their effects on the seedling growth of Salvia miltiorrhiza Bunge and the activities of Solid-Urease (S-UE), Solid-Nitrite Reductase (S-NiR), Solid-Nitrate Reductase (S-NR), Solid-Phosphotransferase (S-PT), and Solid-Catalase (S-CAT), as well as the contents of polysaccharides in the culture medium. The results showed that the growth… More >

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