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  • Open Access

    ARTICLE

    On Multi-Granulation Rough Sets with Its Applications

    Radwan Abu-Gdairi1, R. Mareay2,*, M. Badr3

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1025-1038, 2024, DOI:10.32604/cmc.2024.048647

    Abstract Recently, much interest has been given to multi-granulation rough sets (MGRS), and various types of MGRS models have been developed from different viewpoints. In this paper, we introduce two techniques for the classification of MGRS. Firstly, we generate multi-topologies from multi-relations defined in the universe. Hence, a novel approximation space is established by leveraging the underlying topological structure. The characteristics of the newly proposed approximation space are discussed. We introduce an algorithm for the reduction of multi-relations. Secondly, a new approach for the classification of MGRS based on neighborhood concepts is introduced. Finally, a real-life application from medical records is… More >

  • Open Access

    ARTICLE

    Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome

    JINGJING CHEN1, DAN WANG2, ZEQUN WANG2, MENGYUAN HAN4, HOUQING YIN2, WENTING ZHOU4, RIBAI YAN5, YAN PAN2,3,*

    Oncology Research, Vol.32, No.5, pp. 911-923, 2024, DOI:10.32604/or.2023.042384

    Abstract Photodynamic therapy (PDT) is a promising cancer treatment. This study investigated the antitumor effects and mechanisms of a novel photosensitizer meso-5-[ρ-diethylene triamine pentaacetic acid-aminophenyl]−10,15,20-triphenyl-porphyrin (DTP) mediated PDT (DTP-PDT). Cell viability, reactive oxygen species (ROS), and apoptosis were measured with a Cell Counting Kit-8 assay, DCFH-DA fluorescent probe, and Hoechst staining, respectively. Cell apoptosis- and autophagy-related proteins were examined using western blotting. RNA sequencing was used to screen differentially expressed mRNAs (DERs), and bioinformatic analysis was performed to identify the major biological events after DTP-PDT. Our results show that DTP-PDT inhibited cell growth and induced ROS generation in MCF-7 and SGC7901… More > Graphic Abstract

    Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome

  • Open Access

    ARTICLE

    Dynamic Response of Foundations during Startup of High-Frequency Tunnel Equipment

    Dawei Ruan1, Mingwei Hu1,2,3,4,5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 821-844, 2024, DOI:10.32604/cmes.2024.048392

    Abstract The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale, multifunctional, and complex orientations. The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units, and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts, leading to variations in the dynamic response of the foundation. The high-frequency units yield significantly diverse outcomes under different startup conditions and times, resulting in failure to meet operational requirements, influencing the normal function of the tunnel, and causing harm to the foundation structure, personnel, and property in severe cases. This article… More >

  • Open Access

    ARTICLE

    Knockdown of circular RNA (CircRNA)_001896 inhibits cervical cancer proliferation and stemness in vivo and in vitro

    JIA SHAO1,2, CAN ZHANG2, YAONAN TANG2, AIQIN HE2, WEIPEI ZHU1,*

    BIOCELL, Vol.48, No.4, pp. 571-580, 2024, DOI:10.32604/biocell.2024.049092

    Abstract Objective: Previous studies indicated that aberrant circular RNA (circRNA) expression affects gene expression regulatory networks, leading to the aberrant activation of tumor pathways and promoting tumor cell growth. However, the expression, clinical significance, and effects on cell propagation, invasion, and dissemination of circRNA_001896 in cervical cancer (CC) tissues remain unclear. Methods: The Gene Expression Omnibus (GEO) datasets (GSE113696 and GSE102686) were used to examine differential circRNA expression in CC and adjacent tissues. The expression of circRNA_001896 was detected in 72 CC patients using fluorescence quantitative PCR. Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.… More >

  • Open Access

    REVIEW

    A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

    JHILAM PRAMANIK1,#, AKASH KUMAR2, SARVESH RUSTAGI3,#, MEHAK KATYAL4, SHEETAL THAKUR5, JUTISHNA BORA6, SUMIRA MALIK6,7,*, ANCHAL TREHAN8, NAYAN TALUKDAR9, PETR SLAMA10,*

    BIOCELL, Vol.48, No.4, pp. 541-557, 2024, DOI:10.32604/biocell.2023.029031

    Abstract Many phytochemicals and their derived metabolites produced by plants are extensively employed in commercial goods, pharmaceutical products as well as in the environmental and medical fields. However, these secondary metabolites obtained from plants are in low amounts, and it is difficult to synthesize them at the industrial level. Despite these challenges, they may be utilized for a variety of medicinal products that are either available in the market or are being researched and tested. Secondary metabolites are complex compounds that exhibit chirality. Further, under controlled conditions with elicitors, desired secondary metabolites may be produced from plant cell cultures. This review… More > Graphic Abstract

    A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

  • Open Access

    ARTICLE

    The Influence of Internet Use on Women’s Depression and Its Countermeasures—Empirical Analysis Based on Data from CFPS

    Dengke Xu1, Linlin Shen1, Fangzhong Xu2,*

    International Journal of Mental Health Promotion, Vol.26, No.3, pp. 229-238, 2024, DOI:10.32604/ijmhp.2024.046023

    Abstract Based on China Family Panel Studies (CFPS) 2018 data, the multiple linear regression model is used to analyze the effects of Internet use on women’s depression, and to test the robustness of the regression results. At the same time, the effects of Internet use on mental health of women with different residence, age, marital status and physical health status are analyzed. Then, we can obtain that Internet use has a significant promoting effect on women’s mental health, while the degree of Internet use has a significant inhibitory effect on women’s mental health. In addition, the study found that women’s age,… More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of New Chromophore 4-2-(2-hydroxy-5-(4 nitrophenyl) diazenyl) benzylidene) hydrazinyl) Benzoic Acid and its use in Chitosan Modification

    KAZIM SHAMIM RIZVI, P.K.DUTTA*

    Journal of Polymer Materials, Vol.36, No.1, pp. 75-85, 2019, DOI:10.32381/JPM.2019.36.01.6

    Abstract The present investigation deals with the preparation of carboxylic acid containing new chromophore : 4-2-(2-hydroxy-5-(4-nitrophenyl) diazenyl) benzylidene) hydrazinyl) benzoic acid and its use for chemical modification of chitosan, e.g., chitosan-acid salt complexes under mild conditions. Optical properties of chitosan acid complexes were evaluated by UV and SHG spectroscopy which showed red shift. Antibacterial activity of prepared chitosan acid complexes showed obvious effect against food pathogenic bacteria. The novel polymer complex was soluble in most of the organic solvents. More >

  • Open Access

    ARTICLE

    Swelling dynamics of Poly (N, N- Dimethylacrylamide - co- Crotonic acid) Hydrogel and Evaluation of its Potential for Controlled Release of Fertilizers

    FATMA LOUZRI, SADJIA BENNOUR

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 55-76, 2020, DOI:10.32381/JPM.2020.37.1-2.5

    Abstract Poly(N,N-dimethymethylacrylamide -co-crotonic acid) (P(DMA-CAx)) hydrogels were prepared by free radical polymerization, using N,N- methylenebisacrylamide (NMBA) as cross-linking agent. The synthesized hydrogels were characterized by Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The effects of comonomer composition and pH of the medium on the swelling behavior of hydrogels were investigated. The obtained results showed that the swelling capabilities of hydrogels increased as crotonic acid content and pH increased. In order to evaluate the controlled release potential of the polymeric matrix, it was loaded with potassium nitrate and ammonium nitrate as fertilizers and the release kinetics was studied as a… More >

  • Open Access

    ARTICLE

    Schiff’s base of Fe3O4 @chitosan with 4,4'- diselenobisbenzaldehyde: Preparation, characterization and its catalytic activity for oxidation of sulphides

    RAFAT SABA*, MOHD. KASHIF AZIZ, GHULAM MUSTAFA, ARPIT SRIVASTAVA, SHEKHAR SRIVASTAVA*

    Journal of Polymer Materials, Vol.38, No.1-2, pp. 153-166, 2021, DOI:10.32381/JPM.2021.38.1-2.12

    Abstract We have synthesized Schiff’s base of Fe3 O4 @chitosan with 4,4'-diselenobisbenzaldehyde (Fe3O4 @CSSe) composite and used it as acatalyst for the oxidation of sulfides, having some advantageous properties such as eco-friendly, cost-effective and highly efficient magnetic biocatalyst of selenium. The synthesized schiff’s base was characterized by different physical characterization techniques such as Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), Vibrating sample magnetometer (VSM)and Dynamic light scattering (DLS). Further, we used the resulting schiff’s base as a catalyst in the presence of a green oxidant (H2 O2 ) to oxidize sulfides to corresponding sulfoxides at room temperature. It has been… More >

  • Open Access

    ARTICLE

    Sulfonated Poly (Ether Ether Ketone) and its Blended Nanocomposite for Proton Conducting Membranes

    ABDUL KALAM AZAD1, ARVIND GUPTA3, LAKSHMI UNNIKRISHNAN2,3,*, SMITA MOHANTY3, SANJAY KUMAR NAYAK2,3

    Journal of Polymer Materials, Vol.38, No.1-2, pp. 121-136, 2021, DOI:10.32381/JPM.2021.38.1-2.10

    Abstract Proton conducting hydrophilic channels were created successfully in poly (ether ether ketone) (PEEK) by means of step by step modification followed by the optimization of sulfonation process (SPEEK70, DS=68.57%). Although highly sulfonated PEEK has excellent proton conductivity, it lacks in mechanical stability due to low swelling degree. Therefore, a potential method has been proposed in this work by integrating poly (sulfone) and nanosilica (SiO2 ) into SPEEK matrix. SPEEK 70 (S) was utilized to prepare blended nanocomposite membranes for further enhancement of hydrophilic channels. The blended nanocomposite membranes are, SPEEK/SiO2 as SNS, SPEEK blended with poly (sulfone) as SP, SPEEK… More >

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