BIN LI^1,2,3,#, YUCHENG SHENG^4,#, XIAOYING XU⁴, SHENGCUN WANG³, HONGYAN SONG³, JINGYUAN LI³, HAONAN JI¹, QINGHUA WANG³, XIAODI ZHOU^1,*, LONGJU QI^2,*

BIOCELL, Vol.48, No.4, pp. 601-611, 2024, DOI:10.32604/biocell.2024.047404

Abstract Objective: Chronic kidney disease (CKD) is a progressive disorder characterized by intricate structural and functional alterations in the kidneys, attributable to diverse causative factors. Notably, the therapeutic promise of miR-145-5p in addressing renal pathologies has been discerned. This investigation seeks to elucidate the functional role of miR-145-5p in injured kidneys by subjecting human glomerular mesangial cells (HGMCs) to stimulation with Angiotensin II (AngII). Materials and Methods: Cellular viability and the levels of inflammatory mediators were evaluated utilizing Cell Counting Kit-8 (CCK-8), quantitative real-time polymerase chain reaction (qRT-PCR), and western blot methodologies, both in the presence of AngII incubation and in… More >

Kaiyue Hong, Yasmina Radani, Teja Manda, Jinhui Chen, Liming Yang^*

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 413-425, 2024, DOI:10.32604/phyton.2024.047739

Abstract This study explores CAMTA genes in the rare and endangered Chinese plant species, Liriodendron chinense. Despite the completion of whole-genome sequencing, the roles of CAMTA genes in calcium regulation and stress responses in this species remain largely unexplored. Within the L. chinense genome, we identified two CAMTA genes, Lchi09764 and Lchi222536, characterized by four functional domains: CG-1, TIG, ANK repeats, and IQ motifs. Our analyses, including phylogenetic investigations, cis-regulatory element analyses, and chromosomal location studies, aim to elucidate the defining features of CAMTA genes in L. chinense. Applying Weighted Gene Co-Expression Network Analysis (WGCNA), we explored the impact of CAMTA… More >

Muhammad Farhan^1,#, Manda Sathish², Rafia Kiran¹, Aroosa Mushtaq³, Alaa Baazeem⁴, Ammarah Hasnain⁵, Fahad Hakim¹, Syed Atif Hasan Naqvi^1,#,*, Mustansar Mubeen⁶, Yasir Iftikhar^6,*, Aqleem Abbas⁷, Muhammad Zeeshan Hassan¹, Mahmoud Moustafa⁸

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 581-609, 2024, DOI:10.32604/phyton.2024.046857

Abstract

Plant growth and resilience to abiotic stresses, such as soil salinity and drought, depend intricately on nitrogen metabolism. This review explores nitrogen’s regulatory role in plant responses to these challenges, unveiling a dynamic interplay between nitrogen availability and abiotic stress. In the context of soil salinity, a nuanced relationship emerges, featuring both antagonistic and synergistic interactions between salinity and nitrogen levels. Salinity-induced chlorophyll depletion in plants can be alleviated by optimal nitrogen supplementation; however, excessive nitrogen can exacerbate salinity stress. We delve into the complexities of this interaction and its agricultural implications. Nitrogen, a vital element within essential plant structures… More >

Bing Liu¹, Zhe Zhang¹, Shengrong Hu², Song Sun^3,*, Dapeng Liu⁴, Zhenyu Qiu⁵

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4049-4069, 2024, DOI:10.32604/cmc.2024.048099

Abstract Internet of Things (IoT) is vulnerable to data-tampering (DT) attacks. Due to resource limitations, many anomaly detection systems (ADSs) for IoT have high false positive rates when detecting DT attacks. This leads to the misreporting of normal data, which will impact the normal operation of IoT. To mitigate the impact caused by the high false positive rate of ADS, this paper proposes an ADS management scheme for clustered IoT. First, we model the data transmission and anomaly detection in clustered IoT. Then, the operation strategy of the clustered IoT is formulated as the running probabilities of all ADSs deployed on… More >

Muhammad Umar Nasir¹, Omar Kassem Khalil², Karamath Ateeq³, Bassam SaleemAllah Almogadwy⁴, Muhammad Adnan Khan⁵, Muhammad Hasnain Azam⁶, Khan Muhammad Adnan^7,*

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3303-3321, 2024, DOI:10.32604/cmc.2024.048035

Abstract Cardiotocography measures the fetal heart rate in the fetus during pregnancy to ensure physical health because cardiotocography gives data about fetal heart rate and uterine shrinkages which is very beneficial to detect whether the fetus is normal or suspect or pathologic. Various cardiotocography measures infer wrongly and give wrong predictions because of human error. The traditional way of reading the cardiotocography measures is the time taken and belongs to numerous human errors as well. Fetal condition is very important to measure at numerous stages and give proper medications to the fetus for its well-being. In the current period Machine learning… More >

Hong Huang¹, Xingxing Zhang^1,*, Ye Lu¹, Ze Li¹, Shaohua Zhou²

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3929-3951, 2024, DOI:10.32604/cmc.2024.047918

Abstract While encryption technology safeguards the security of network communications, malicious traffic also uses encryption protocols to obscure its malicious behavior. To address the issues of traditional machine learning methods relying on expert experience and the insufficient representation capabilities of existing deep learning methods for encrypted malicious traffic, we propose an encrypted malicious traffic classification method that integrates global semantic features with local spatiotemporal features, called BERT-based Spatio-Temporal Features Network (BSTFNet). At the packet-level granularity, the model captures the global semantic features of packets through the attention mechanism of the Bidirectional Encoder Representations from Transformers (BERT) model. At the byte-level granularity,… More >

Yilei Wang¹, Xin Sun¹, Guiping Zheng^2,3, Ahmar Rashid⁴, Sami Ullah⁵, Hisham Alasmary⁶, Muhammad Waqas^7,8,*

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3909-3927, 2024, DOI:10.32604/cmc.2024.047767

Abstract The application of Intelligent Internet of Things (IIoT) in constructing distribution station areas strongly supports platform transformation, upgrade, and intelligent integration. The sensing layer of IIoT comprises the edge convergence layer and the end sensing layer, with the former using intelligent fusion terminals for real-time data collection and processing. However, the influx of multiple low-voltage in the smart grid raises higher demands for the performance, energy efficiency, and response speed of the substation fusion terminals. Simultaneously, it brings significant security risks to the entire distribution substation, posing a major challenge to the smart grid. In response to these challenges, a… More >

Jin Wang^1,2, Guoshu Huang¹, R. Simon Sherratt³, Ding Huang⁴, Jia Ni^4,*

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4029-4048, 2024, DOI:10.32604/cmc.2024.047468

Abstract With the development of Industry 4.0 and big data technology, the Industrial Internet of Things (IIoT) is hampered by inherent issues such as privacy, security, and fault tolerance, which pose certain challenges to the rapid development of IIoT. Blockchain technology has immutability, decentralization, and autonomy, which can greatly improve the inherent defects of the IIoT. In the traditional blockchain, data is stored in a Merkle tree. As data continues to grow, the scale of proofs used to validate it grows, threatening the efficiency, security, and reliability of blockchain-based IIoT. Accordingly, this paper first analyzes the inefficiency of the traditional blockchain… More >

Muhammad Saad¹, Muhammad Raheel Bhutta², Jongik Kim^3,*, Tae-Sun Chung¹

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4263-4282, 2024, DOI:10.32604/cmc.2024.047132

Abstract With the increase in IoT (Internet of Things) devices comes an inherent challenge of security. In the world today, privacy is the prime concern of every individual. Preserving one’s privacy and keeping anonymity throughout the system is a desired functionality that does not come without inevitable trade-offs like scalability and increased complexity and is always exceedingly difficult to manage. The challenge is keeping confidentiality and continuing to make the person innominate throughout the system. To address this, we present our proposed architecture where we manage IoT devices using blockchain technology. Our proposed architecture works on and off blockchain integrated with… More >

Talal Albalawi, P. Ganeshkumar^*

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3511-3528, 2024, DOI:10.32604/cmc.2024.046396

Abstract The Internet of Things (IoT) is a growing technology that allows the sharing of data with other devices across wireless networks. Specifically, IoT systems are vulnerable to cyberattacks due to its opennes The proposed work intends to implement a new security framework for detecting the most specific and harmful intrusions in IoT networks. In this framework, a Covariance Linear Learning Embedding Selection (CL2ES) methodology is used at first to extract the features highly associated with the IoT intrusions. Then, the Kernel Distributed Bayes Classifier (KDBC) is created to forecast attacks based on the probability distribution value precisely. In addition, a… More >