ZHANSHU LIU1, XI HUANG2,*
BIOCELL, Vol.47, No.3, pp. 593-605, 2023, DOI:10.32604/biocell.2023.024148
- 03 January 2023
Abstract Purpose: Iron metabolism maintains the balance between iron absorption and excretion. Abnormal iron
metabolism can cause numerous diseases, including tumor. This study determined the iron metabolism-related genes
(IMRGs) signature that can predict the prognosis of acute myeloid leukemia (AML). The roles of these genes in the
immune microenvironment were also explored. Methods: A total of 514 IMRGs were downloaded from the
Molecular Characteristics Database (MSigDB). IMRGs related to AML prognosis were identified using Cox regression
and LASSO analyses and were used to construct the risk score model. AML patients were stratified into high-risk
groups (cluster 1)… More >
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