Zhenjiang Li^*1, Chenyang Xu^*1, Ming Gao^*, Bingqian Ding^*, Xinting Wei^†, Nan Ji^‡

Oncology Research, Vol.25, No.3, pp. 365-372, 2017, DOI:10.3727/096504016X14738135889976

Abstract Jumonji AT-rich interactive domain 2 (JARID2) is a member of the Jumonji family of proteins and has been proposed as an oncogene in several types of human cancer. However, the role of JARID2 in human glioma has not yet been understood. The present study was designed to determine the roles of JARID2 in the proliferation and migration in human glioma cells and the growth of glioma cells in nude mice. Our data indicate that JARID2 is upregulated in human glioma tissues and cell lines. Knockdown of JARID2 obviously inhibits the proliferation of U87MG cells and More >

AJIT C. DHADVE^1,2, PRITHA RAY^1,2

BIOCELL, Vol.46, No.1, pp. 75-86, 2022, DOI:10.32604/biocell.2022.016346

Abstract Progression, relapse, and therapy resistance are the most challenging features of cancer therapy that have been postulated to be driven by Cancer Stem Cell (CSC) population. This enigmatic subpopulation of cancer cells has therefore emerged as promising therapeutic candidate. We earlier reported enrichment of CSC-like side population (SP) with increasing resistance towards Cisplatin and Paclitaxel either alone or in combination in epithelial ovarian cancer (EOC) cells. This SP population is a small proportion of the total population of cancer cells characterised with high expression of drug transporters, a unique feature of stem cells and thereby… More >

Shahan Yamin Siddiqui^1,2, Sagheer Abbas¹, Muhammad Adnan Khan^3,*, Iftikhar Naseer⁴, Tehreem Masood⁴, Khalid Masood Khan³, Mohammed A. Al Ghamdi⁵, Sultan H. Almotiri⁵

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1719-1732, 2021, DOI:10.32604/cmc.2020.012585

Abstract The prompt spread of Coronavirus (COVID-19) subsequently adorns a big threat to the people around the globe. The evolving and the perpetually diagnosis of coronavirus has become a critical challenge for the healthcare sector. Drastically increase of COVID-19 has rendered the necessity to detect the people who are more likely to get infected. Lately, the testing kits for COVID-19 are not available to deal it with required proficiency, along with-it countries have been widely hit by the COVID-19 disruption. To keep in view the need of hour asks for an automatic diagnosis system for early… More >