Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (2,305)
  • Open Access

    ARTICLE

    Combined Wind-Storage Frequency Modulation Control Strategy Based on Fuzzy Prediction and Dynamic Control

    Weiru Wang1, Yulong Cao1,*, Yanxu Wang1, Jiale You1, Guangnan Zhang1, Yu Xiao2

    Energy Engineering, Vol.121, No.12, pp. 3801-3823, 2024, DOI:10.32604/ee.2024.055398 - 22 November 2024

    Abstract To ensure frequency stability in power systems with high wind penetration, the doubly-fed induction generator (DFIG) is often used with the frequency fast response control (FFRC) to participate in frequency response. However, a certain output power suppression amount (OPSA) is generated during frequency support, resulting in the frequency modulation (FM) capability of DFIG not being fully utilised, and the system’s unbalanced power will be increased during speed recovery, resulting in a second frequency drop (SFD) in the system. Firstly, the frequency response characteristics of the power system with DFIG containing FFRC are analysed. Then, based… More >

  • Open Access

    ARTICLE

    AI-Driven Prioritization and Filtering of Windows Artifacts for Enhanced Digital Forensics

    Juhwan Kim, Baehoon Son, Jihyeon Yu, Joobeom Yun*

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 3371-3393, 2024, DOI:10.32604/cmc.2024.057234 - 18 November 2024

    Abstract Digital forensics aims to uncover evidence of cybercrimes within compromised systems. These cybercrimes are often perpetrated through the deployment of malware, which inevitably leaves discernible traces within the compromised systems. Forensic analysts are tasked with extracting and subsequently analyzing data, termed as artifacts, from these systems to gather evidence. Therefore, forensic analysts must sift through extensive datasets to isolate pertinent evidence. However, manually identifying suspicious traces among numerous artifacts is time-consuming and labor-intensive. Previous studies addressed such inefficiencies by integrating artificial intelligence (AI) technologies into digital forensics. Despite the efforts in previous studies, artifacts were… More >

  • Open Access

    REVIEW

    AI-Powered Innovations in High-Tech Research and Development: From Theory to Practice

    Mitra Madanchian1,*, Hamed Taherdoost1,2,3,4

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2133-2159, 2024, DOI:10.32604/cmc.2024.057094 - 18 November 2024

    Abstract This comparative review explores the dynamic and evolving landscape of artificial intelligence (AI)-powered innovations within high-tech research and development (R&D). It delves into both theoretical models and practical applications across a broad range of industries, including biotechnology, automotive, aerospace, and telecommunications. By examining critical advancements in AI algorithms, machine learning, deep learning models, simulations, and predictive analytics, the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies. The review integrates both qualitative and quantitative data derived from academic studies, industry reports, and real-world case studies to showcase the… More >

  • Open Access

    ARTICLE

    Using Multi-Omics Analysis to Explore Diagnostic Tool and Optimize Drug Therapy Selection for Patients with Glioma Based on Cross-Talk Gene Signature

    YUSHI YANG1,#, CHUJIAO HU2,#, SHAN LEI3, XIN BAO3, ZHIRUI ZENG3,*, WENPENG CAO4,*

    Oncology Research, Vol.32, No.12, pp. 1921-1934, 2024, DOI:10.32604/or.2024.046191 - 13 November 2024

    Abstract Background: The heterogeneity of prognosis and treatment benefits among patients with gliomas is due to tumor microenvironment characteristics. However, biomarkers that reflect microenvironmental characteristics and predict the prognosis of gliomas are limited. Therefore, we aimed to develop a model that can effectively predict prognosis, differentiate microenvironment signatures, and optimize drug selection for patients with glioma. Materials and Methods: The CIBERSORT algorithm, bulk sequencing analysis, and single-cell RNA (scRNA) analysis were employed to identify significant cross-talk genes between M2 macrophages and cancer cells in glioma tissues. A predictive model was constructed based on cross-talk gene expression, and… More >

  • Open Access

    ARTICLE

    LncRNA AFAP1-AS1 exhibits oncogenic characteristics and promotes gemcitabine-resistance of cervical cancer cells through miR-7-5p/EGFR axis

    CHAOQUN WANG1, TING ZHANG2, CHAOHE ZHANG3,*

    Oncology Research, Vol.32, No.12, pp. 1867-1879, 2024, DOI:10.32604/or.2024.044547 - 13 November 2024

    Abstract Background: Drug resistance is the main factor contributing to cancer recurrence and poor prognosis. Exploration of drug resistance-related mechanisms and effective therapeutic targets are the aim of molecular targeted therapy. In our study, the role of long non-coding RNA (lncRNA) AFAP1-AS1 in gemcitabine resistance and related mechanisms were explored in cervical cancer cells. Methods: Gemcitabine-resistant cervical cancer cell lines HT-3-Gem and SW756-Gem were constructed using the gemcitabine concentration gradient method. The overall survival rates and recurrence-free survival rates were evaluated by Kaplan-Meier analysis. The interaction was verified through a Dual-luciferase reporter gene assay and a… More > Graphic Abstract

    LncRNA AFAP1-AS1 exhibits oncogenic characteristics and promotes gemcitabine-resistance of cervical cancer cells through miR-7-5p/EGFR axis

  • Open Access

    PROCEEDINGS

    Towards High-Fidelity and Efficient Computation for Diagnosis and Treatment of Cardiovascular Disease

    Lei Wang1,*, Blanca Rodriguez2, Xiaoyu Luo3, Charles Augarde4

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.013350

    Abstract Cardiovascular disease is the leading cause of death worldwide. Disease-specific software, like FFRct from HeartFlow, and high-fidelity computational models within a general-purpose software, like Living Heart Project within Abaqus, are essential to revolutionise diagnosis and treatment of cardiovascular disease for clinicians and design of medical devices for industries. This talk presents our past researches on computational modelling of tear propagation in the aortic dissection [1-2] and of electromechanical coupling in the human heart with the finite element method [3], and our current exploration on high-fidelity and efficient computation and software development for diagnosis and treatment More >

  • Open Access

    PROCEEDINGS

    Integrated Multiscale Unified Phase-Field Modellings (UPFM)

    Yuhong Zhao1,2,3,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012951

    Abstract For a long time, the phase-field method has been considered as a mesoscale phenomenological method lacking physical accuracy and unable to be associated with the mechanical/functional properties of materials, etc. Some misunderstandings existing in these viewpoints need to be clarified. Therefore, it is necessary to propose or adopt the perspective of “unified or unifying phase-field modeling (UPFM)” to address these issues, which means that phase-field modeling has multiple unifications. Specifically, the phase-field method is the perfect unity of thermodynamics and kinetics, the unity of multi-scale models from micro- to meso- and then to macroscopic scale, More >

  • Open Access

    REVIEW

    The roles and mechanisms of miRNA in HBV-HCC carcinogenesis: Why no therapeutic agents after 30 years?

    KURT SARTORIUS1,2,3,*, BENN SARTORIUS4, CHERIE WINKLER5, ANIL CHUTURGOON2, ANNA KRAMVIS1, PING AN5, WEIGANG ZHANG6, YUNJIE LU3,6,7,*

    BIOCELL, Vol.48, No.11, pp. 1543-1567, 2024, DOI:10.32604/biocell.2024.055505 - 07 November 2024

    Abstract Hepatitis B-associated hepatocellular carcinoma (HBV-HCC) remains an intractable high-mortality solid tumor cancer that accounted for 42% of global HCC cases in 2019. Despite some developments in systemic therapy, only a small subset of late-stage HCC patients responds positively to recently developed therapeutic innovations. MicroRNAs (miRNAs) act as an ancillary epigenetic system that can regulate genome expression in all cancer pathways including HCC. The molecular mechanisms of miRNA regulation in cancer pathogenesis offered researchers a new approach that was widely hoped would translate into miRNA-based drugs and diagnostics. Thirty years on, miRNA-based diagnostic and therapeutic agents… More >

  • Open Access

    REVIEW

    Advances in micropillar arrays in cellular biomechanics detection and tissue engineering

    XUELING HE, LINLU JIN, YIXUE QIN, JIAN ZHONG, ZHI OUYANG, YE ZENG*

    BIOCELL, Vol.48, No.11, pp. 1521-1529, 2024, DOI:10.32604/biocell.2024.055410 - 07 November 2024

    Abstract Cellular biomechanical features contributed to the occurrence and development of various physiological and pathological phenomena. Micropillar arrays have emerged as an important tool for both the assessment and manipulation of cellular biomechanical characteristics. This comprehensive review provides an in-depth understanding of the fabrication methodologies of micropillar arrays and their applications in deciphering and fine-tuning cellular biomechanical properties and the innovative experimental platforms including organ-on-a-chip and organoids-on-a-chip. This review provides novel insights into the potential of micropillar technology, poised to update the landscape of stem cell research and tissue engineering. More >

  • Open Access

    ARTICLE

    Ganoderic acid A ameliorates renal fibrosis by suppressing the expression of NPC1L1

    TIANYUN HAN#, ZHONG LI#, LUONING ZHANG, LINSHEN XIE*

    BIOCELL, Vol.48, No.11, pp. 1625-1638, 2024, DOI:10.32604/biocell.2024.055029 - 07 November 2024

    Abstract Objective: The study aimed to explore the protective mechanism of Ganoderic acid A (GAA) in renal fibrosis and to verify that GAA can ameliorate renal fibrosis by regulating the Niemann-pick C1-like 1 (NPC1L1) gene. Methods: Transforming growth factor beta1 (TGF-β1) was used to treat Human Kidney-2 (HK-2) cells to establish a renal fibrosis model. The differentially expressed genes in the control (CTRL) group, TGF-β1 group, and TGF-β1 + GAA group were screened via transcriptome sequencing technology and verified by qPCR and Western blot experiments. The NPC1L1 gene overexpression plasmid was constructed. The expression levels of N-cad, E-cad,… More >

Displaying 1-10 on page 1 of 2305. Per Page