Sabrina Meddah^1,2,*, Sid Ahmed Tadjer³, Abdelhakim Idir⁴, Kong Fah Tee^5,6,*, Mohamed Zinelabidine Doghmane¹, Madjid Kidouche¹

Structural Durability & Health Monitoring, Vol.19, No.1, pp. 77-103, 2025, DOI:10.32604/sdhm.2024.053541 - 15 November 2024

Abstract Maintaining the integrity and longevity of structures is essential in many industries, such as aerospace, nuclear, and petroleum. To achieve the cost-effectiveness of large-scale systems in petroleum drilling, a strong emphasis on structural durability and monitoring is required. This study focuses on the mechanical vibrations that occur in rotary drilling systems, which have a substantial impact on the structural integrity of drilling equipment. The study specifically investigates axial, torsional, and lateral vibrations, which might lead to negative consequences such as bit-bounce, chaotic whirling, and high-frequency stick-slip. These events not only hinder the efficiency of drilling… More >

SAM SON¹, AKSHAAR BRAHMBHATT¹, KEN ZHAO¹, BRETT MARINELLI¹, JAMES HARDING², WILLIAM JARNAGIN³, GHASSAN K. ABOU-ALFA², HOOMAN YARMOHAMMADI^1,*

Oncology Research, Vol.32, No.12, pp. 1831-1836, 2024, DOI:10.32604/or.2024.052985 - 13 November 2024

Abstract Background: This article aims to present the single-institution outcomes of patients with Fibrolamellar Carcinoma (FLC) treated with liver-directed therapies (LDT). Methods: In this single-center retrospective study, all patients diagnosed with FLC who underwent LDT were identified. Between July 2012 and July 2023, six patients were identified. One patient was excluded due to bleeding. Demographic and clinical parameters were recorded. Complications within 30 days of the LDT were evaluated. Radiological treatment responses at 1, 6, and 12 months were assessed per mRECIST. Results: A total of five patients, which included three females and two males, were reviewed.… More >

TIANYUN HAN^#, ZHONG LI^#, LUONING ZHANG, LINSHEN XIE^*

BIOCELL, Vol.48, No.11, pp. 1625-1638, 2024, DOI:10.32604/biocell.2024.055029 - 07 November 2024

Abstract Objective: The study aimed to explore the protective mechanism of Ganoderic acid A (GAA) in renal fibrosis and to verify that GAA can ameliorate renal fibrosis by regulating the Niemann-pick C1-like 1 (NPC1L1) gene. Methods: Transforming growth factor beta1 (TGF-β1) was used to treat Human Kidney-2 (HK-2) cells to establish a renal fibrosis model. The differentially expressed genes in the control (CTRL) group, TGF-β1 group, and TGF-β1 + GAA group were screened via transcriptome sequencing technology and verified by qPCR and Western blot experiments. The NPC1L1 gene overexpression plasmid was constructed. The expression levels of N-cad, E-cad,… More >

ZEYIN LAI¹, HANGYUAN ZHAO¹, HONG DENG^1,2,*

BIOCELL, Vol.48, No.11, pp. 1569-1578, 2024, DOI:10.32604/biocell.2024.053983 - 07 November 2024

Abstract In the development of colorectal cancer (CRC), cancer-associated fibroblasts (CAFs) play a pivotal role in establishing tumor-permissive extracellular matrix structures, angiogenesis, and modulating the immune status of the tumor microenvironment (TME), thereby influencing tumor metastasis and resistance to radiotherapy and chemotherapy. The pleiotropic effects of CAFs in the TME may be attributed to the heterogeneous origin and high plasticity of their population. Given the specificity of CAFs, they provide a variety of potential target molecules for future CRC treatment, which may play an indispensable role in CRC therapeutic strategies. This review summarizes the origin of More >

Tatyana Lyubimova^1,2,*, Yulia Garicheva², Andrey Ivantsov¹

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.11, pp. 2417-2429, 2024, DOI:10.32604/fdmp.2024.052391 - 28 October 2024

Abstract External vibrations are known to be one of the promising ways to control the behavior of multiphase systems. The computational modeling of the behavior of a gas bubble in a viscous liquid in a horizontal cylinder of square cross-section, which undergoes linearly polarized translational oscillations in weightless conditions, has been carried out. Under vibrations, the bubble moves towards the wall of the vessel with acceleration determined by the amplitudes and frequency of vibrations. Near the wall, at a distance of the order of the thickness of the viscous Stokes boundary layer, the effects of viscosity More >

Vladimir Konovalov^*

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.11, pp. 2541-2563, 2024, DOI:10.32604/fdmp.2024.051219 - 28 October 2024

Abstract The regime of horizontal subcooled film boiling is characterized by the formation of a thin layer of vapor covering the surface of a flat horizontal heater. Based on the equations of motion of a viscous incompressible fluid and the equation of heat transfer, the stability of such a vapor film is investigated. The influence of the modulation of the gravity field caused by vertical vibrations of the heater of finite frequency, as well as a constant electric field applied normal to the surface of the heater, is taken into account. It is shown that in… More >

Chongdong Lin^1,2,3,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011631

Abstract In many real-world scenarios, such as high-speed combustion processes and re-entry flows in aerospace vehicles, the flow conditions often involve complex interactions between multiple chemical species and energy modes, leading to thermodynamic nonequilibrium effects. Traditional computational fluid dynamics (CFD) methods struggle to accurately capture these phenomena due to their simplifying assumptions regarding equilibrium thermodynamics. To solve this issue, the Multicomponent Discrete Boltzmann Method (MDBM) is proposed as a numerical approach to simulate compressible reactive flows with thermodynamic nonequilibrium effects. Based on kinetic theory, this method can capture the complex interactions between different species and energy… More >

Binjie Mu¹, Jun Liu^2,*, Yuanfang Chen¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.011110

Abstract With the improvement of aircraft design requirements, the development of airborne equipment towards lightweight, miniaturization and weight reduction has brought great challenges to the structural design of airborne equipment. Usually, airborne equipment needs to be connected to the fuselage through supporting brackets. In the process of airplane flight, due to the influence of vibration and other complex load conditions, the mounting bracket of airborne equipment is prone to damage caused by the unreasonable structural design of airborne equipment. Some sensitive airborne electronic equipment has special requirements for the dynamic characteristics of the bracket. Therefore, the… More >

Kirill Rysin^*

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.10, pp. 2235-2249, 2024, DOI:10.32604/fdmp.2024.052324 - 23 September 2024

Abstract The study of average convection in a rotating cavity subjected to modulated rotation is an interesting area for the development of both fundamental and applied science. This phenomenon finds application in the field of mass transfer and fluid flow control, relevant examples being crystal growth under reduced gravity and fluid mixing in microfluidic devices for cell cultures. In this study, the averaged flow generated by the oscillating motion of a fluid in a planar layer rotating about a horizontal axis is experimentally investigated. The boundaries of the layer are maintained at constant temperatures, while the… More >

Giada Faraco, Andrea Vincenzo De Nunzio, Nicola Ivan Giannoccaro^*, Arcangelo Messina

Structural Durability & Health Monitoring, Vol.18, No.6, pp. 739-762, 2024, DOI:10.32604/sdhm.2024.052663 - 20 September 2024

Abstract The possibility of determining the integrity of a real structure subjected to non-invasive and non-destructive monitoring, such as that carried out by a series of accelerometers placed on the structure, is certainly a goal of extreme and current interest. In the present work, the results obtained from the processing of experimental data of a real structure are shown. The analyzed structure is a lattice structure approximately 9 m high, monitored with 18 uniaxial accelerometers positioned in pairs on 9 different levels. The data used refer to continuous monitoring that lasted for a total of 1… More >