Bin Zhang1, Na Li1, Hao Zhang
Oncology Research, Vol.26, No.1, pp. 37-44, 2018, DOI:10.3727/096504017X14900530835262
Abstract Homeobox B5 (HOXB5), a member of the HOX gene family, has been shown to play an important role in
tumor progression. However, the expression and functional role of HOXB5 in human non-small cell lung cancer
(NSCLC) have not been defined. Thus, the purpose of this study was to elucidate the expression and functional
role of HOXB5 in human NSCLC. Our results showed that HOXB5 expression was elevated in human NSCLC
tissues and cell lines. The in vitro experiments demonstrated that knockdown of HOXB5 inhibited proliferation,
migration, and invasion and prevented the EMT phenotype in NSCLC More >
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