Yidong Cao*1, Liang Zhang*1, Minghao Wei*, Xue Jiang†, Dong Jia*
Oncology Research, Vol.25, No.7, pp. 1097-1107, 2017, DOI:10.3727/096504017X14836170586829
Abstract Emerging evidence has suggested that aberrantly expressed microRNAs (miRNAs) are associated with glioma
development and progression. The aberrant expression of miR-409-3p has been reported in several human cancers. However, little is known about the function of miR-409-3p in gliomas. The aim of this study was to investigate the specific role and molecular mechanism of miR-409-3p in gliomas. In the present study, we found
that miR-409-3p was downregulated in glioma tissue and cell lines. Overexpression of miR-409-3p inhibited
glioma cell invasion and proliferation, whereas suppression of miR-409-3p promoted glioma cell invasion
and proliferation. High-mobility group nucleosome-binding More >
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