Saifei He*1, Guangdong Wang†1, Jing Ni*, Juhua Zhuang*, Suiliang Zhuang‡, Guoyu Wang*, Ying Ye*, Wei Xia*
Oncology Research, Vol.26, No.9, pp. 1355-1363, 2018, DOI:10.3727/096504018X15154094331876
Abstract Dysregulated microRNA (miRNA) expression is involved in the occurrence and development of colorectal
cancer (CRC) through the regulation of various important physiological events. Hence, miRNAs may be used
as effective targets for CRC treatment; however, this hypothesis warrants further investigation. miRNA-511
(miR-511) plays vital roles in the progression of different tumor types. However, the expression, exact role,
and the mechanisms underlying the regulation of colorectal carcinogenesis and progression by miR-511 remain
poorly understood. This study presents that miR-511 expression was decreased in CRC tissues and cell lines
compared with that in adjacent nonneoplastic tissues and More >
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