LEI SUN1,2, YUE ZHANG3, YUQIN YAO4, HONGLIN DU3, YUEHUA ZHANG1, AIPING FANG1,2,*
Oncology Research, Vol.29, No.3, pp. 175-187, 2021, DOI:10.32604/or.2022.03550
- 01 August 2022
Abstract Long intergenic non-protein coding RNA 1124 (LINC01124) has been identified as an important regulator of
non-small-cell lung cancer. However, the expression and detailed role of LINC01124 in hepatocellular carcinoma (HCC)
remain unestablished to date. Therefore, this study aimed to elucidate the role of LINC01124 in the aggressiveness of
HCC cells and identify the underlying regulatory mechanism. Quantitative reverse transcriptase-polymerase chain
reaction was performed to measure the expression of LINC01124 in HCC. Cell Counting Kit-8 assay, Transwell cell
migration and invasion assays, and a xenograft tumor model were used to investigate the function of LINC01124 in… More >