Wei Wang, Ke Zheng, Yi Pei, XiaoJing Zhang
Oncology Research, Vol.26, No.3, pp. 373-384, 2018, DOI:10.3727/096504017X14939809845080
Abstract JARID1B has been proven to be upregulated in many human malignancies and is correlated with tumor progression. However, its expression and clinical significance in osteosarcoma are still unclear. Thus, the aim of
this study was to explore the effects of JARID1B in osteosarcoma tumorigenesis and development. In this
study, we found that the expression levels of JARID1B in osteosarcoma tissues were significantly higher than
those in corresponding noncancerous bone tissues. In addition, JARID1B upregulation occurred more frequently in osteosarcoma specimens from patients with a poor prognosis. After JARID1B transfection in osteosarcoma cells, cell proliferation was More >
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