Xiaoliang Zhao1,#, Yuting Wang1,#, Xiuying Pu1, Jianzhong Ma1, Feifan Leng1, Yonggang Wang1, Yanling Wang1, Shuhong Yang1, Fen Ran2, Weijie Zhang1,*
Journal of Renewable Materials, Vol.7, No.12, pp. 1321-1332, 2019, DOI:10.32604/jrm.2019.07757
Abstract A series of the Guiqi polysaccharides/chitosan/alginate composite
hydrogel microspheres (GPcM) with different particle sizes were prepared with
Guiqi polysaccharides (GP), chitosan (CS) and sodium alginate (Alg). The
optimum preparation process was also determined by single factor and
orthogonal experiment analysis. The GPcM were characterized by fourier
transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM),
drug loading efficiency test (LE), encapsulation efficiency test (EE) and in vitro
release study. The results showed that the Guiqi polysaccharides chitosan
hydrogel (GPCH) and sodium alginate hydrogel (SAH) formed a crossover
system in GPcM. The GPcM have a uniform particle More >