FREDERICK H. SILVER^1,2,*, TANMAY DESHMUKH²

BIOCELL, Vol.48, No.4, pp. 525-540, 2024, DOI:10.32604/biocell.2024.047965

Abstract All tissues in the body are subjected externally to gravity and internally by collagen fibril and cellular retractive forces that create stress and energy equilibrium required for homeostasis. Mechanotransduction involves mechanical work (force through a distance) and energy storage as kinetic and potential energy. This leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue components. It involves the application of energy directly to cells through integrin-mediated processes, cell-cell connections, stretching of the cell cytoplasm, and activation of the cell nucleus via yes-associated protein (YAP) and transcriptional coactivator with PDZ-motif (TAZ). These processes involve numerous… More >

S. DEIVANAYAKI^1,*, P. JAYAMURUGAN², S. ASHOKAN³, V. GOPALA KRISHNAN⁴, B. YOGESWARI⁵

Journal of Polymer Materials, Vol.38, No.3-4, pp. 295-307, 2021, DOI:10.32381/JPM.2021.38.3-4.10

Abstract The cholesterol level determination is a significant clinical diagnostic solution for heart and, thrombosis problems. In this work, we examined a novel non-enzymatic cholesterol biosensor using cholesterol oxidase (ChOx) enzyme immobilized on TiO₂ nanoparticles influenced by reduced graphene oxide (rGO) - polypyrrole (PPy) (rGO-TiO₂ /PPy-GCE) nanocomposite was developed on a glassy carbon electrode (GCE) and the higher sensing response with lower detection limits were observed. The electrochemical properties of GCE modified PPy (PPy-GCE) were studied using CV (Cyclic Voltammetry) and DPV (Differential Pulse Voltammetry). The reported sensor exhibited piecewise linearity in the range of 0.1 µM to 1 µM and… More >

Lei Liang, Xiangyang Hu^*

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 517-531, 2024, DOI:10.32604/phyton.2024.049277

Abstract With the rapid development of modern molecular biology and bioinformatics, many studies have proved that transcription factors play an important role in regulating the growth and development of plants. SPATULA (SPT) belongs to the bHLH transcription family and participates in many processes of regulating plant growth and development. This review systemically summarizes the multiple roles of SPT in plant growth, development, and stress response, including seed germination, flowering, leaf size, carpel development, and root elongation, which is helpful for us to better understand the functions of SPT. More >

Rui Zhang¹, Taixiang Chen¹, Zhenjiang Chen¹, Hao Chen¹, Xuekai Wei¹, Malik Kamran¹, Chunjie Li^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 567-580, 2024, DOI:10.32604/phyton.2024.047485

Abstract In a greenhouse experiment, the effects of soil microorganisms and extracts of Achnatherum inebrians on the seed germination and seedling growth of Elymus nutans were studied. The results showed that both the extracts from aboveground and belowground parts of A. inebrians significantly inhibited the germination rate, germination potential, germination index, vigor index, seedling height, root length, and fresh weight of E. nutans, but increased malondialdehyde content, catalase, peroxidase and superoxide dismutase activity of E. nutans seedlings (p < 0.05). The allelopathy of aqueous extracts of the aboveground parts of A. inebrians was stronger than that of the precipitates. Aqueous extracts… More >

Jai Hak Park^*

Digital Engineering and Digital Twin, Vol.2, pp. 79-101, 2024, DOI:10.32604/dedt.2024.047280

Abstract A finite element alternating method has been known as a very convenient and accurate method to solve two and three-dimensional crack problems. In this method, a general crack problem is solved by a superposition of two solutions. One is a finite element solution for a finite body without a crack, and the other is an analytical solution for a crack in an infinite body. Since a crack is not considered in a finite element model, generating a model is very simple. The method is especially very convenient for a fatigue crack growth simulation. Over the past 40 years, S. N.… More >

Eduardo Burgos-Valencia^1,#, Federico García-Laynes^1,#, Ileana Echevarría-Machado¹, Fatima Medina-Lara¹, Miriam Monforte-González¹, José Narváez-Zapata^2,*, Manuel Martínez-Estévez^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.2, pp. 151-183, 2024, DOI:10.32604/phyton.2023.046943

Abstract Habanero pepper (Capsicum chinense Jacq.) is a crop of economic relevance in the Peninsula of Yucatan. Its fruits have a high level of capsaicinoids compared to peppers grown in other regions of the world, which gives them industrial importance. Soil is an important factor that affects pepper development, nutritional quality, and capsaicinoid content. However, the effect of soil type on fruit development and capsaicinoid metabolism has been little understood. This work aimed to compare the effect of soils with contrasting characteristics, black soil (BS) and red soil (RS), on the expression of genes related to the development of fruits, and… More >

JINNI MA^#, MEILIN ZHOU^#, XIN XU, XINYAO GAO, HAIXIA WANG, JINHUA SHEN, LU XUE^*

BIOCELL, Vol.48, No.2, pp. 239-252, 2024, DOI:10.32604/biocell.2023.045076

Abstract Background: Placenta specific 8 (PLAC8) is a candidate oncogene involved in the development and progression of solid tumors. However, the status of PLAC8 in lung cancer (LC), especially non-small cell lung cancer (NSCLC) is still not lucid. Methods: Tissue microarray analysis (TMA) was performed to detect the expression patterns of PLAC8 in LC tissues and cell lines. Then a series of cellular experiments were performed fto assess cell proliferation, cell cycle profiles, and cell motility to explore the role of PLAC8 in NSCLC-derived cell lines: H1299 and A549. Results: TMA results showed that PLAC8 played complex and even contradictory roles… More >

YUANYUAN XU, XIAOKE CHEN^*

Oncology Research, Vol.32, No.3, pp. 517-528, 2024, DOI:10.32604/or.2023.030293

Abstract Background: The aberrant intracellular expression of a mitochondrial aspartyl-tRNA synthetase 2 (DARS2) has been reported in human cancers. Nevertheless, its critical role and detailed mechanism in lung adenocarcinoma (LUAD) remain unexplored. Methods: Initially, The Cancer Genome Atlas (TCGA)-based Gene Expression Profiling Interactive Analysis (GEPIA) database () was used to analyze the prognostic relevance of DARS2 expression in LUAD. Further, cell counting kit (CCK)-8, immunostaining, and transwell invasion assays in LUAD cell lines in vitro, as well as DARS2 silence on LUAD by tumorigenicity experiments in vivo in nude mice, were performed. Besides, we analyzed the expression levels of p-PI3K (phosphorylated-Phosphotylinosital3… More >

DAOLUN YU¹, DEYONG SHE², KAI GE¹, LEI YANG¹, RUINA ZHAN¹, SHAN LU^3,*, YAFEI CAI^4,*

BIOCELL, Vol.48, No.1, pp. 139-147, 2024, DOI:10.32604/biocell.2023.045884

Abstract Background: SMAD family proteins (SMADs) are crucial transcription factors downstream of transforming growth factor beta (TGF-ß)/SMAD signaling pathways that have been reported to play a pivotal role in mammalian reproduction. However, the role of SMAD family member 8 (SMAD8, also known as SMAD9), a member of the SMAD family, in mammalian reproduction remains unclear. Methods: We employed RNA interference techniques to knock down Smad8 expression in mouse granulosa cells (GCs) to investigate the effects of Smad8 on GC growth and steroidogenesis. Results: Our findings revealed a significant decrease in the proliferative capacity and a substantial increase in the apoptosis rate… More >

Anyin Qi^1,#, Xiaonan Yan^1,#, Yuqing Liu^1,#, Qingchen Zeng¹, Hang Yuan¹, Huange Huang¹, Chenggang Liang², Dabing Xiang¹, Liang Zou¹, Lianxin Peng¹, Gang Zhao¹, Jingwei Huang^1,*, Yan Wan^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 1-13, 2024, DOI:10.32604/phyton.2023.045802

Abstract

Aluminum (Al) toxicity is a considerable factor limiting crop yield and biomass in acidic soil. Tartary buckwheat growing in acidic soil may suffer from Al poisoning. Here, we investigated the influence of Al stress on the growth of tartary buckwheat seedling roots, and the alleviation of Al stress by silicon (Si), as has been demonstrated in many crops. Under Al stress, root growth (total root length, primary root length, root tips, root surface area, and root volume) was significantly inhibited, and Al and malondialdehyde (MDA) accumulated in the root tips. At the same time, catalase (CAT) and ascorbate peroxidase activities,… More >