Mian LIU1, Xumeng ZHANG2, *
BIOCELL, Vol.41, No.1, pp. 19-26, 2017, DOI:10.32604/biocell.2017.41.019
Abstract Bladder, kidney, prostate and testicular carcinoma are the top four genitourinary cancers in China. Here
we analyzed mRNA and miRNA expression profiles of carcinomas of the bladder (TCC), kidney (ccRCC) and testis
(TGCT) to uncover their specific regulatory mechanisms. The gene expression profiles of GSE31617 were downloaded
from GEO database, which contained 27 samples, including 10 TCC, 7 TGCT and 10 ccRCC. Specific up- and downregulated differentially expressed genes (DEGs) and differentially expressed microRNAs (DEmiRNAs) of each
cancer were selected and target genes of DEmiRNAs were predicted. Gene interaction network of the shared
genes and… More >