Yue-shen Wang*1, Jing Tian†1, Yong Han†, Shu-mei Han†, Sheng-bin Shi†
Oncology Research, Vol.24, No.2, pp. 129-135, 2016, DOI:10.3727/096504016X14618564639213
Abstract We evaluated the efficacy and feasibility of the combination of gemcitabine plus vinorelbine in patients with
platinum-based chemotherapy-refractory esophageal cancer. We enrolled 35 patients who received gemcitabine plus vinorelbine as second-line treatment after platinum-based chemotherapy failure between May 2009
and April 2012. Dosage: gemcitabine 1,000 mg/m2
plus vinorelbine 25 mg/m2
; all drugs were administered
on days 1 and 8 of a 21-day cycle, and this was continued until failure or unacceptable toxicity. A total of 125
cycles of treatment were administered, and all patients received at least two cycles of treatment (two to five
cycles;… More >