Jianyu Zhou*, Xiaorong Li*, Meirong Wu†, Changwei Lin*, Yihang Guo*, Buning Tian*
Oncology Research, Vol.23, No.6, pp. 303-309, 2015, DOI:10.3727/096504016X14567549091305
Abstract Emerging evidence has identified the vital role of long noncoding RNAs (lncRNAs) in the development of
colorectal cancer. In this study, we aimed to investigate the role of lncRNA gastric carcinoma highly expressed
transcript 1 (GHET1) in colorectal cancer. We analyzed the expression of GHET1 in colorectal cancer (CRC)
tissues by using ISH. We found that GHET1 expression was significantly increased in the CRC samples
compared with adjacent tissues. Furthermore, the cancer tissues had higher GHET1 mRNA levels than their
matched adjacent tissues. GHET1 expression was also significantly increased in the CRC cell lines compared More >